The extent of Skeletal muscle wasting in prolonged critical illness and its association with survival: insights from a retrospective single-center study.

Journal: BMC anesthesiology
Published Date: May 26, 2025

Abstract

OBJECTIVE: Muscle wasting in critically ill patients, particularly those with prolonged hospitalization, poses a significant challenge to recovery and long-term outcomes. The aim of this study was to characterize long-term muscle wasting trajectories in ICU patients with acute respiratory distress syndrome (ARDS) due to COVID-19 and acute pancreatitis (AP), to evaluate correlations between muscle wasting and patient outcomes, and to identify clinically feasible thresholds that have the potential to enhance patient care strategies.

Authors

  • Johannes Kolck
    Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany. Johannes.kolck@charite.de.
  • Clarissa Hosse
    Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
  • Uli Fehrenbach
    Department of Diagnostic and Interventional Radiology, Charité -Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
  • Nick-Lasse Beetz
    Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
  • Timo Alexander Auer
    Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
  • Christian Pille
    Department of Anesthesiology and Intensive Care Medicine| CCM| CVK, Charité- Universitätsmedizin Berlin, Berlin, Germany.
  • Dominik Geisel
    Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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