Mechanistic study of Lonicerae Japonicae Flos (Caprifoliaceae) in non-small cell lung cancer prevention and treatment through integrative pharmacology, multi-machine learning, artificial intelligence, and in vitro experiments.

Journal: Journal of ethnopharmacology
Published Date: Apr 17, 2025

Abstract

ETHNOPHARMACOLOGICAL RELEVANCE: Lonicerae Japonicae Flos (Caprifoliaceae) (LJF), an herb with the homology of medicine and food, is traditionally utilized for its heat-clearing, detoxifying, and anticancer properties. Yet, the mechanism by which LJF may assist in the treatment of non-small cell lung cancer (NSCLC) remains unclear.

Authors

  • Can Liu
    School of Medical Informatics Engineering, Anhui University of Chinese Medicine, Hefei, Anhui 230012, China.
  • Peng He
    Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, PR China.
  • Ru Qiao
    College of Pharmacy, Hunan University of Chinese Medicine, Changsha, 410208, China; Hunan Provincial Key Laboratory of Drugability and Preparation Modification of TCM, Changsha, 410208, China. Electronic address: 2604806572@qq.com.
  • Xiaoyan Yang
  • Changsong Ding
    School of Informatics, Hunan University of Chinese Medicine, Changsha, Hunan, 410208, China. Electronic address: dingcs1975@hnucm.edu.cn.
  • Fuyuan He
    College of Pharmacy, Hunan University of Chinese Medicine, Changsha, 410208, China; Hunan Provincial Key Laboratory of Drugability and Preparation Modification of TCM, Changsha, 410208, China. Electronic address: pharmsharking@163.com.

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