Antibacterial effects of thyme oil loaded solid lipid and chitosan nano-carriers against Salmonella Typhimurium and Escherichia coli as food preservatives.

Journal: PloS one
PMID:

Abstract

OBJECTIVES: Escherichia coli and Salmonella Typhimurium are frequent causes of foodborne illness affecting many people annually. In order to develop natural antimicrobial agents against these microorganisms, thyme oil (TO) was considered as active antibacterial ingredient. TO contains various bioactive compounds that exhibit antimicrobial properties. To increase the antibacterial effects and stability of thyme oil, two promising carrier systems, solid lipid nanoparticles (SLN) and chitosan nanoparticles have been fabricated in this study.

Authors

  • Amirhosein Shabgoo Monsef
    Department of Pharmaceutics, School of Pharmacy, Guilan University of Medical Sciences, Rasht, Iran.
  • Mehran Nemattalab
    Department of Pharmaceutics, School of Pharmacy, Guilan University of Medical Sciences, Rasht, Iran.
  • Shirin Parvinroo
    Department of Pharmacognosy, School of Pharmacy, Guilan University of Medical Sciences, Rasht, Iran.
  • Zahra Hesari
    Department of Pharmaceutics, School of Pharmacy, Guilan University of Medical Sciences, Rasht, Iran.