AIMC Topic: Chitosan

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Machine learning-integrated electrochemical sensing of ciprofloxacin for digital point-of-care therapeutic drug monitoring.

Mikrochimica acta
Timely and precise therapeutic drug monitoring (TDM) is critical for managing pharmacokinetic variability and optimizing individualized therapy, particularly during public health crises such as the COVID-19 pandemic. Herein, we optimized integrated m...

Anthocyanins loaded bilayer films based on polysaccharides assisted by machine learning for fish freshness monitoring.

Food chemistry
Novel multifunctional packaging for monitoring and maintaining food freshness has been developed. Bilayer films based on polysaccharides incorporating red cabbage anthocyanins were prepared. Anthocyanins were encapsulated in the inner layer based on ...

Flexible Porous ACH/Ag Surface-Enhanced Raman Scattering Platform for Sensitive Detection and Machine-Learning-Assisted Classification of Multiple Pathogenic Bacteria.

Analytical chemistry
Pathogenic bacteria pose serious threats to public health and environmental safety. Conventional colony counting, a standard method for bacterial detection, is time-consuming and unsuitable for rapid on-site detection. In this work, a flexible ACH/Ag...

3D-printed chitosan-starch mesh filled with minocycline-alginate hydrogel for dual anti-Staphylococcus aureus and osteogenic effects.

Carbohydrate polymers
Bone infections, particularly those caused by Staphylococcus aureus, pose clinical challenges due to biofilm formation and association with bone loss. To address this, we developed a three-dimensional (3D) printed hydrogel-based drug delivery device ...

Biomacromolecular engineering of redox-active chitosan-polypyrrole-clay hybrid materials for machine learning-assisted desulfurization and supercapacitor application.

International journal of biological macromolecules
The bentonite chitosan polypyrrole (Bent-CS-PPy) composite was engineered as a multifunctional material with dual capabilities: the efficient adsorption of dibenzothiophene (DBT) from model fuel and application as an electrode in electrochemical ener...

Machine learning framework for oxytetracycline removal using nanostructured cupric oxide supported on magnetic chitosan alginate biocomposite.

Scientific reports
This research proposes a machine learning controlled method for removing the antibiotic oxytetracycline (OTC) from liquids through the use of nanostructured cupric oxide (CuO) nanoparticles. These nanoparticles are attached to magnetic chitosan/algin...

Machine learning modeling and response surface methodology driven antioxidant and anticancer activities of chitosan nanoparticle-mediated extracts of Bacopa monnieri.

International journal of biological macromolecules
This study investigates the potential of chitosan nanoparticles (CNPs) in enhancing the bioavailability and efficacy of Bacopa monnieri extracts, known for their neuroprotective, antioxidant, and anticancer properties. Different concentrations of CNP...

Prediction of newly synthesized heparin mimic's effects as heparanase inhibitor in cancer treatments via variational quantum neural networks.

Computational biology and chemistry
Cancer remains a leading global cause of death, primarily driven by the uncontrolled proliferation of abnormal cells. Malignant tumors, such as carcinomas, originate from unchecked epithelial cell growth and produce growth factors like FGF and VEGF, ...

Deep eutectic solvent-modified polyvinyl alcohol/chitosan thin film membrane for dye adsorption: Machine learning modeling, experimental, and density functional theory calculations.

International journal of biological macromolecules
The polyvinyl alcohol/chitosan (PVA/CS) thin film membrane was modified using a deep eutectic solvent (DES) to enhance its adsorption capability and mechanical strength for the removal of brilliant green (BG) dye. Batch adsorption experiments, machin...

Antibacterial effects of thyme oil loaded solid lipid and chitosan nano-carriers against Salmonella Typhimurium and Escherichia coli as food preservatives.

PloS one
OBJECTIVES: Escherichia coli and Salmonella Typhimurium are frequent causes of foodborne illness affecting many people annually. In order to develop natural antimicrobial agents against these microorganisms, thyme oil (TO) was considered as active an...