Effects of Renal Function on the Multimodal Brain Networks Affecting Mild Cognitive Impairment Converters in End-Stage Renal Disease.

Journal: Academic radiology
Published Date: Apr 3, 2025

Abstract

RATIONALE AND OBJECTIVES: Cognitive decline is common in End-Stage Renal Disease (ESRD) patients, yet its neural mechanisms are poorly understood. This study investigates structural and functional brain network reconfiguration in ESRD patients transitioning to Mild Cognitive Impairment (MCI) and evaluates its potential for predicting MCI risk.

Authors

  • ZiYang Yu
    School of Medicine, Xiamen University, Xiamen, 361000, Fujian, PR China.
  • Yinke Du
    Department of Nephrology, First Affiliated Hospital of China Medical University, Shenyang, Liaoning Province, China (Z.Y., Y.D., L.Y.). Electronic address: kerk1982@163.com.
  • HuiZe Pang
    Department of Radiology, The First Affiliated Hospital of China Medical University, Shenyang, 110001, Liaoning, PR China. Electronic address: ophelia0702@163.com.
  • Xiaolu Li
    Department of Rehabilitation Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, China.
  • Yu Liu
    Research Center of Information Technology, Beijing Academy of Agriculture and Forestry Science, Beijing, China.
  • Shuting Bu
    Department of Radiology, First Affiliated Hospital of China Medical University, Shenyang, Liaoning Province, China (H.P., X.L., Y.L., S.B., J.W., M.Z., X.L.). Electronic address: bushuting66@163.com.
  • Juzhou Wang
    Department of Radiology, First Affiliated Hospital of China Medical University, Shenyang, Liaoning Province, China (H.P., X.L., Y.L., S.B., J.W., M.Z., X.L.). Electronic address: WangjuzhouWJZ@163.com.
  • Mengwan Zhao
    Department of Radiology, First Affiliated Hospital of China Medical University, Shenyang, Liaoning Province, China (H.P., X.L., Y.L., S.B., J.W., M.Z., X.L.). Electronic address: zmwcabbage@163.com.
  • Zhenghong Ren
    Department of Ophthalmology, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China (Z.R.). Electronic address: 13002463792@163.com.
  • Xuedan Li
    Department of Radiology, First Affiliated Hospital of China Medical University, Shenyang, Liaoning Province, China (H.P., X.L., Y.L., S.B., J.W., M.Z., X.L.). Electronic address: xuedan1225@sina.com.
  • Li Yao
    College of Information Science and Technology, Beijing Normal University, Beijing, China.

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