External validation of a machine learning prediction model for massive blood loss during surgery for spinal metastases: a multi-institutional study using 880 patients.

Journal: The spine journal : official journal of the North American Spine Society
Published Date: Mar 27, 2025

Abstract

BACKGROUND CONTEXT: A machine learning (ML) model was recently developed to predict massive intraoperative blood loss (>2,500 mL) during posterior decompressive surgery for spinal metastasis that performed well on external validation within the same region in China.

Authors

  • Daniël C de Reus
    Department of Orthopedic Surgery, Massachusetts General Hospital - Harvard Medical School, 55 Fruit St, Room 3.932, Yawkey building, Boston, MA 02114, USA; Department of Radiation Oncology, University Medical Center Utrecht, Polikliniek Radiotherapie, UMC Utrecht, P.O. Box 85500, 3508 GA, Utrecht, the Netherlands. Electronic address: danieldereus@outlook.com.
  • René Harmen Kuijten
    Department of Radiation Oncology, University Medical Center Utrecht, Polikliniek Radiotherapie, UMC Utrecht, P.O. Box 85500, 3508 GA, Utrecht, the Netherlands.
  • Priyanshu Saha
    Department of Orthopedic Surgery, St. George's University Hospitals, NHS Foundation Trust, Department of Spinal Surgery, Neurosciences, Atkinson Morley Wing, St. George's Hospital, Blackshaw Rd, SW17 0QT, London, UK.
  • Diego A Abelleyra Lastoria
    Department of Orthopedic Surgery, St. George's University Hospitals, NHS Foundation Trust, Department of Spinal Surgery, Neurosciences, Atkinson Morley Wing, St. George's Hospital, Blackshaw Rd, SW17 0QT, London, UK.
  • Aliénor Warr-Esser
    Department of Orthopedic Surgery, St. George's University Hospitals, NHS Foundation Trust, Department of Spinal Surgery, Neurosciences, Atkinson Morley Wing, St. George's Hospital, Blackshaw Rd, SW17 0QT, London, UK.
  • Charles F C Taylor
    Department of Orthopedic Surgery, St. George's University Hospitals, NHS Foundation Trust, Department of Spinal Surgery, Neurosciences, Atkinson Morley Wing, St. George's Hospital, Blackshaw Rd, SW17 0QT, London, UK.
  • Olivier Q Groot
    Department of Orthopedic Surgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St, Boston, MA 02114, USA.
  • Darren Lui
    Department of Orthopedic Surgery, St. George's University Hospitals, NHS Foundation Trust, Department of Spinal Surgery, Neurosciences, Atkinson Morley Wing, St. George's Hospital, Blackshaw Rd, SW17 0QT, London, UK.
  • Jorrit-Jan Verlaan
    P. T. Ogink, J.-J. Verlaan, Department of Orthopaedic Surgery, University Medical Center Utrecht, Utrecht, the Netherlands.
  • Daniel G Tobert
    Department of Orthopedic Surgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St, Boston, MA 02114, USA.

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