AIMC Topic: Spinal Neoplasms

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A machine learning tool for prediction of vertebral compression fracture following stereotactic body radiation therapy for spinal metastases.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: The most common adverse event following spine stereotactic body radiotherapy (SBRT) is vertebral compression fracture (VCF). There is interest in the development of patient-specific tools that can predict those at high risk of...

Risk calculator for long-term survival prediction of spinal chordoma versus chondrosarcoma: a nationwide analysis.

Journal of neuro-oncology
PURPOSE: Chordomas and chondrosarcomas are rare, aggressive spinal bone tumors with distinct origins, biological behavior, and treatment challenges, primarily due to their resistance to conventional chemotherapy and radiation. This study aimed to com...

Towards real-time conformal palliative treatment of spine metastases: A deep learning approach for Hounsfield Unit recovery of cone beam CT images.

Medical physics
BACKGROUND: The extension of onboard cone-beam CT (CBCT) imaging for real-time treatment planning is constrained by limitations in image quality. Synthetic CT (sCT) generation using deep learning provides a potential solution to these limitations.

External validation of a machine learning prediction model for massive blood loss during surgery for spinal metastases: a multi-institutional study using 880 patients.

The spine journal : official journal of the North American Spine Society
BACKGROUND CONTEXT: A machine learning (ML) model was recently developed to predict massive intraoperative blood loss (>2,500 mL) during posterior decompressive surgery for spinal metastasis that performed well on external validation within the same ...

Predicting quality of life of patients after treatment for spinal metastatic disease: development and internal evaluation.

The spine journal : official journal of the North American Spine Society
BACKGROUND CONTEXT: When treating spinal metastases in a palliative setting, maintaining or enhancing quality of life (QoL) is the primary therapeutic objective. Clinicians tailor their treatment strategy by weighing the QoL benefits against expected...

Development and evaluation of a deep learning framework for pelvic and sacral tumor segmentation from multi-sequence MRI: a retrospective study.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: Accurate segmentation of pelvic and sacral tumors (PSTs) in multi-sequence magnetic resonance imaging (MRI) is essential for effective treatment and surgical planning.

Direct-to-Treatment Adaptive Radiation Therapy: Live Planning of Spine Metastases Using Novel Cone Beam Computed Tomography.

International journal of radiation oncology, biology, physics
PURPOSE: Cone beam computed tomography (CBCT)-based online adaptive radiation therapy is carried out using a synthetic CT (sCT) created through deformable registration between the patient-specific fan-beam CT, fan-beam computed tomography (FBCT), and...

External validation of 12 existing survival prediction models for patients with spinal metastases.

The spine journal : official journal of the North American Spine Society
BACKGROUND CONTEXT: Survival prediction models for patients with spinal metastases may inform patients and clinicians in shared decision-making.