The human infertility single-cell testis atlas (HISTA): an interactive molecular scRNA-Seq reference of the human testis.

Journal: Andrology
Published Date: Apr 5, 2024

Abstract

BACKGROUND: Single-cell RNA-seq (scRNA-Seq) has been widely adopted to study gene expression of the human testis. Several datasets of scRNA-Seq from human testis have been generated from different groups processed with different informatics pipelines. An integrated atlas of scRNA-Seq expression constructed from multiple donors, developmental ages, and fertility states would be widely useful for the testis research community.

Authors

  • Eisa Mahyari
    Division of Genetics, Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, USA.
  • Katinka A Vigh-Conrad
    Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Portland, OR, United States.
  • Clément Daube
    Division of Genetics, Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, USA.
  • Ana C Lima
    Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Portland, OR, United States.
  • Jingtao Guo
    Andrology and IVF Laboratory, Division of Urology, Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah, USA.
  • Douglas T Carrell
    Andrology and IVF Laboratory, Division of Urology, Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah, USA.
  • James M Hotaling
    Division of Urology, Department of Surgery, University of Utah, Salt Lake City, Utah.
  • Kenneth I Aston
    Andrology and IVF Laboratory, Division of Urology, Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah, USA.
  • Donald F Conrad
    Division of Genetics, Oregon National Primate Research Center, Oregon Health and Science University, Portland, OR, United States.

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