Transcriptomics-based exploration of ubiquitination-related biomarkers and potential molecular mechanisms in laryngeal squamous cell carcinoma.

Journal: BMC medical genomics
PMID:

Abstract

BACKGROUND: One of the most common and prevalent cancers is laryngeal squamous cell carcinoma (LSCC), which poses a great threat to the life and health of the patient. Nonetheless, it has been demonstrated that ubiquitination is crucial for the development and course of LSCC. Therefore, it is particularly important to identify biomarkers for ubiquitination-related genes (UbRGs) in LSCC.

Authors

  • Qiu Chen
    Department of Endocrinology, The Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
  • Zhimin Wu
    School of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou, 550004, China.
  • Yifei Ma
    Department of Otorhinolaryngology, Affiliated Hospital of Guizhou Medical University, 28 Guiyi Street, Yunyan District, Guiyang, Guizhou, 550004, China. mayifei@gmc.edu.cn.