AIMC Topic: Laryngeal Neoplasms

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Identification of DSC2 as a Key Biomarker for Induction Chemotherapy Sensitivity in Locally Advanced Laryngeal and Hypopharyngeal Squamous Cell Carcinoma.

Journal of chemical information and modeling
Patients with locally advanced laryngeal and hypopharyngeal squamous cell carcinoma (LA-LHSCC) urgently need precise treatment strategies to improve the prognosis due to severe laryngeal functional impairment following traditional surgery and chemora...

Metabolic profiles in laryngeal cancer defined two distinct molecular subtypes with divergent prognoses.

Frontiers in immunology
BACKGROUND: Laryngeal cancer (LCA) is the second most common type of head and neck malignancy, characterized by high recurrence rates and poor overall survival (OS). However, progress in curing LCA through molecular-targeted diagnostics and therapies...

Personalized therapeutic strategies and prognosis for advanced laryngeal squamous cell carcinoma: Insights from machine learning models.

American journal of otolaryngology
PURPOSE: Despite the development of diverse treatment options, there has been an increase in mortality rates for laryngeal squamous cell carcinoma (LSCC). Our research employed survival analysis and machine learning (ML) techniques to evaluate the im...

Investigating the key principles in two-step heterogeneous transfer learning for early laryngeal cancer identification.

Scientific reports
Data scarcity in medical images makes transfer learning a common approach in computer-aided diagnosis. Some disease classification tasks can rely on large homogeneous public datasets to train the transferred model, while others cannot, i.e., endoscop...

Comparable Performance Between Automatic and Manual Laryngeal and Hypopharyngeal Gross Tumor Volume Delineations Validated With Pathology.

International journal of radiation oncology, biology, physics
PURPOSE: Deep learning is a promising approach to increase reproducibility and time-efficiency of gross tumor volume (GTV) delineation in head and neck cancer, but model evaluation primarily relies on manual GTV delineations as reference annotation, ...

Construction of prediction model of early glottic cancer based on machine learning.

Acta oto-laryngologica
BACKGROUND: The early diagnosis of glottic laryngeal cancer is the key to successful treatment, and machine learning (ML) combined with narrow-band imaging (NBI) laryngoscopy provides a new idea for the early diagnosis of glottic laryngeal cancer.

Machine learning in personalized laryngeal cancer management: insights into clinical characteristics, therapeutic options, and survival predictions.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
PURPOSE: Over the last 40 years, there has been an unusual trend where, even though there are more varied treatments, survival rates have not improved much. Our study used survival analysis and machine learning (ML) to investigate this odd situation ...

Application of artificial intelligence in laryngeal lesions: a systematic review and meta-analysis.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
OBJECTIVE: The objective of this systematic review and meta-analysis was to evaluate the diagnostic accuracy of AI-assisted technologies, including endoscopy, voice analysis, and histopathology, for detecting and classifying laryngeal lesions.

Self-Attention Mechanisms-Based Laryngoscopy Image Classification Technique for Laryngeal Cancer Detection.

Head & neck
BACKGROUND: The early diagnosis of laryngeal cancer (LCA) is crucial for prognosis, driving our search for an accurate, precise, and sensitive deep learning model to assist in LCA detection.