AIMC Topic: Laryngeal Neoplasms

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CT-based radiomics and deep learning models for predicting thyroid cartilage invasion and patient prognosis in laryngeal carcinoma.

Scientific reports
Accurate assessment of thyroid cartilage invasion is crucial for treatment decision-making and prognosis evaluation in laryngeal squamous cell carcinoma (LSCC). This study aimed to compare the performance of the radiomics and deep learning (DL) model...

Multi-channel deep learning radiomics model based on contrast-enhanced CT for predicting postoperative prognosis in laryngeal carcinoma.

BMC cancer
BACKGROUND: Accurate prediction of prognosis and risk stratification in patients with laryngeal cancer can inform appropriate treatment decision-making. This study aims to develop a multi-channel deep learning radiomics model based on contrast-enhanc...

A Vision-Language-Guided Multimodal Fusion Network for Glottic Carcinoma Early Diagnosis: Model Development and Validation Study.

JMIR medical informatics
BACKGROUND: Early diagnosis and intervention in glottic carcinoma (GC) can significantly improve long-term prognosis. However, the accurate diagnosis of early GC is challenging due to its morphological similarity to vocal cord dysplasia, with the dif...

Use of a Preliminary Artificial Intelligence-Based Laryngeal Cancer Screening Framework for Low-Resource Settings: Development and Validation Study.

JMIR formative research
BACKGROUND: Early-stage diagnosis of laryngeal cancer significantly improves patient survival and quality of life. However, the scarcity of specialists in low-resource settings hinders the timely review of flexible nasopharyngoscopy (FNS) videos, whi...

Identification of DSC2 as a Key Biomarker for Induction Chemotherapy Sensitivity in Locally Advanced Laryngeal and Hypopharyngeal Squamous Cell Carcinoma.

Journal of chemical information and modeling
Patients with locally advanced laryngeal and hypopharyngeal squamous cell carcinoma (LA-LHSCC) urgently need precise treatment strategies to improve the prognosis due to severe laryngeal functional impairment following traditional surgery and chemora...

Metabolic profiles in laryngeal cancer defined two distinct molecular subtypes with divergent prognoses.

Frontiers in immunology
BACKGROUND: Laryngeal cancer (LCA) is the second most common type of head and neck malignancy, characterized by high recurrence rates and poor overall survival (OS). However, progress in curing LCA through molecular-targeted diagnostics and therapies...

Single-View Contrastive Learning for Laryngeal Leukoplakia Classification With NBI Laryngoscopy Images.

Head & neck
BACKGROUND: Laryngeal cancer is the second most common upper respiratory tract cancer. Early and accurate diagnosis can improve the cure rate of patients. Laryngoscopy with NBI is a commonly used tool that can help endoscopists diagnose laryngeal dis...

Personalized therapeutic strategies and prognosis for advanced laryngeal squamous cell carcinoma: Insights from machine learning models.

American journal of otolaryngology
PURPOSE: Despite the development of diverse treatment options, there has been an increase in mortality rates for laryngeal squamous cell carcinoma (LSCC). Our research employed survival analysis and machine learning (ML) techniques to evaluate the im...

Investigating the key principles in two-step heterogeneous transfer learning for early laryngeal cancer identification.

Scientific reports
Data scarcity in medical images makes transfer learning a common approach in computer-aided diagnosis. Some disease classification tasks can rely on large homogeneous public datasets to train the transferred model, while others cannot, i.e., endoscop...