Refined prognostication of pathological complete response in breast cancer using radiomic features and optimized InceptionV3 with DCE-MRI.
Journal:
Scientific reports
Published Date:
Jul 30, 2025
Abstract
BACKGROUND: Neoadjuvant therapy plays a pivotal role in breast cancer treatment, particularly for patients aiming to conserve their breast by reducing tumor size pre-surgery. The ultimate goal of this treatment is achieving a pathologic complete response (pCR), which signifies the complete eradication of cancer cells, thereby lowering the likelihood of recurrence. This study introduces a novel predictive approach to identify patients likely to achieve pCR using radiomic features extracted from MR images, enhanced by the InceptionV3 model and cutting-edge validation methodologies.
