Fusion model integrating multi-sequence MRI radiomics and habitat imaging for predicting pathological complete response in breast cancer treated with neoadjuvant therapy.

Journal: Cancer imaging : the official publication of the International Cancer Imaging Society
Published Date:

Abstract

BACKGROUND: This study aimed to develop a predictive model integrating multi-sequence MRI radiomics, deep learning features, and habitat imaging to forecast pathological complete response (pCR) in breast cancer patients undergoing neoadjuvant therapy (NAT).

Authors

  • Shaojie Xu
    Department of Thyroid and Breast Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, People's Republic of China.
  • Yushi Ying
    Department of Thyroid and Breast Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, People's Republic of China.
  • Qilan Hu
    Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, People's Republic of China.
  • Xingyin Li
    Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People's Republic of China.
  • Yulin Li
    Department of Physics, and Fujian Provincial Key Laboratory for Soft Functional Materials Research, Xiamen University, Xiamen 361005, China.
  • Hao Xiong
  • Yanyan Chen
    School of Materials Science and Engineering, Peking University, Beijing 100871, China.
  • Qing Ye
    School of Computer Science and Technology, Wuhan University of Technology, Wuhan 430000, China.
  • Xingrui Li
    Department of Thyroid and Breast Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, People's Republic of China.
  • Yue Liu
    School of Athletic Performance, Shanghai University of Sport, Shanghai, China.
  • Tao Ai
    Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou District, Wuhan, 430030, People's Republic of China.
  • Yaying Du
    Department of Thyroid and Breast Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, People's Republic of China. yayingdu@hust.edu.cn.