Identification of necroptotic biomarkers associated with immune microenvironment in sepsis based on the protein-protein interaction network and machine learning.
Journal:
Clinica chimica acta; international journal of clinical chemistry
Published Date:
Jul 14, 2025
Abstract
BACKGROUND: Necroptosis is inflammatorily sparked and closely associated with sepsis, but the crosstalk between necroptosis and inflammation in sepsis has rarely been studied in depth. This study is designed to reveal the role of necroptosis in the pathogenesis and development of sepsis by screening and validating hub necroptotic septic genes.
