Deep learning-based post-hoc noise reduction improves quarter-radiation-dose coronary CT angiography.

Journal: European journal of radiology
Published Date: Jun 9, 2025

Abstract

PURPOSE: To evaluate the impact of deep learning-based post-hoc noise reduction (DLNR) on image quality, coronary artery disease reporting and data system (CAD-RADS) assessment, and diagnostic performance in quarter-dose versus full-dose coronary CT angiography (CCTA) on external datasets.

Authors

  • Tomoro Morikawa
    Department of Radiology, National Cerebral and Cardiovascular Center, 6-1, Kishibe-Shimmachi, Suita, Osaka, 564-8565, Japan.
  • Tatsuya Nishii
    From the Department of Radiology, National Cerebral and Cardiovascular Center, 6-1 Kishibe-shinmachi, Suita 564-8565, Japan (T.N., T.K., H.T., A.K., Y.O., Y.M., H.H., T.F.); Department of Medical Physics and Engineering, Graduate School of Medicine, Osaka University, Suita, Japan (T.K., K.U., J.O., T.I.); Medical Informatics Section, QST Hospital (K.U., J.O.), and Applied MRI Research, Department of Molecular Imaging and Theranostics, Institute for Quantum Medical Science (K.U., J.O.), National Institutes for Quantum Science and Technology, Chiba, Japan.
  • Yuki Tanabe
    Department of Radiology, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, 791-0295, Japan. yuki.tanabe.0225@gmail.com.
  • Kazuki Yoshida
    Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
  • Wataru Toshimori
    Department of Radiology, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, Japan.
  • Naoki Fukuyama
    Department of Radiology, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, 791-0295, Japan.
  • Hidetaka Toritani
    Ehime University School of Medicine, Shitsukawa, Toon City, Japan.
  • Hiroshi Suekuni
    Department of Radiology, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, Japan.
  • Tetsuya Fukuda
    From the Department of Radiology, National Cerebral and Cardiovascular Center, 6-1 Kishibe-shinmachi, Suita 564-8565, Japan (T.N., T.K., H.T., A.K., Y.O., Y.M., H.H., T.F.); Department of Medical Physics and Engineering, Graduate School of Medicine, Osaka University, Suita, Japan (T.K., K.U., J.O., T.I.); Medical Informatics Section, QST Hospital (K.U., J.O.), and Applied MRI Research, Department of Molecular Imaging and Theranostics, Institute for Quantum Medical Science (K.U., J.O.), National Institutes for Quantum Science and Technology, Chiba, Japan.
  • Teruhito Kido
    Department of Radiology, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, 791-0295, Japan.

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