Integration of a prognostic gene module with a drug sensitivity module to identify drugs that could be repurposed for breast cancer therapy.

Journal: Computers in biology and medicine
PMID: 25596797

Abstract

BACKGROUND: Efficiently discovering low risk drugs is important for drug development. However, the heterogeneity in patient population complicates the prediction of the therapeutic efficiency. Drug repositioning aiming to discover new indications of known drugs provides a possible gateway.

Authors

  • Lida Zhu
    Key State Laboratory of Software Engineering, School of Computer, Wuhan University, Wuhan 430072, PR China.
  • Juan Liu
    Key State Laboratory of Software Engineering, School of Computer, Wuhan University, Wuhan 430072, PR China. Electronic address: liujuan@whu.edu.cn.

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