Automatic learning-based beam angle selection for thoracic IMRT.

Journal: Medical physics
Published Date:

Abstract

PURPOSE: The treatment of thoracic cancer using external beam radiation requires an optimal selection of the radiation beam directions to ensure effective coverage of the target volume and to avoid unnecessary treatment of normal healthy tissues. Intensity modulated radiation therapy (IMRT) planning is a lengthy process, which requires the planner to iterate between choosing beam angles, specifying dose-volume objectives and executing IMRT optimization. In thorax treatment planning, where there are no class solutions for beam placement, beam angle selection is performed manually, based on the planner's clinical experience. The purpose of this work is to propose and study a computationally efficient framework that utilizes machine learning to automatically select treatment beam angles. Such a framework may be helpful for reducing the overall planning workload.

Authors

  • Guy Amit
    Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, Ontario M5G 2M9, Canada.
  • Thomas G Purdie
    Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, Ontario M5G 2M9, Canada; Department of Radiation Oncology, University of Toronto, Toronto, Ontario M5S 3E2, Canada; and Techna Institute, University Health Network, Toronto, Ontario M5G 1P5, Canada.
  • Alex Levinshtein
    Department of Computer Science, University of Toronto, Toronto, Ontario M5S 3G4, Canada.
  • Andrew J Hope
    Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, Ontario M5G 2M9, Canada and Department of Radiation Oncology, University of Toronto, Toronto, Ontario M5S 3E2, Canada.
  • Patricia Lindsay
    Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, Ontario M5G 2M9, Canada and Department of Radiation Oncology, University of Toronto, Toronto, Ontario M5S 3E2, Canada.
  • Andrea Marshall
    Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, Ontario M5G 2M9, Canada.
  • David A Jaffray
    Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, Ontario M5G 2M9, Canada; Department of Radiation Oncology, University of Toronto, Toronto, Ontario M5S 3E2, Canada; and Techna Institute, University Health Network, Toronto, Ontario M5G 1P5, Canada.
  • Vladimir Pekar
    Philips Healthcare, Markham, Ontario L6C 2S3, Canada.