A support vector machine tool for adaptive tomotherapy treatments: Prediction of head and neck patients criticalities.

Journal: Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Published Date:

Abstract

PURPOSE: Adaptive radiation therapy (ART) is an advanced field of radiation oncology. Image-guided radiation therapy (IGRT) methods can support daily setup and assess anatomical variations during therapy, which could prevent incorrect dose distribution and unexpected toxicities. A re-planning to correct these anatomical variations should be done daily/weekly, but to be applicable to a large number of patients, still require time consumption and resources. Using unsupervised machine learning on retrospective data, we have developed a predictive network, to identify patients that would benefit of a re-planning.

Authors

  • Gabriele Guidi
    Medical Physics Department, Az. Ospedaliero-Universitaria di Modena, Italy; Physics Department, University of Bologna, Italy. Electronic address: guidi.gabriele@policlinico.mo.it.
  • Nicola Maffei
    Medical Physics Department, Az. Ospedaliero-Universitaria di Modena, Italy; Physics Department, University of Bologna, Italy.
  • Claudio Vecchi
    Physics Department, University of Bologna, Italy.
  • Alberto Ciarmatori
    Medical Physics Department, Az. Ospedaliero-Universitaria di Modena, Italy; Post-graduate School in Medical Physics, University of Bologna, Italy.
  • Grazia Maria Mistretta
    Medical Physics Department, Az. Ospedaliero-Universitaria di Modena, Italy.
  • Giovanni Gottardi
    Medical Physics Department, Az. Ospedaliero-Universitaria di Modena, Italy.
  • Bruno Meduri
    Radiation Oncology Department, Az. Ospedaliero-Universitaria di Modena, Italy.
  • Giuseppe Baldazzi
    Physics Department, University of Bologna, Italy.
  • Filippo Bertoni
    Radiation Oncology Department, Az. Ospedaliero-Universitaria di Modena, Italy.
  • Tiziana Costi
    Medical Physics Department, Az. Ospedaliero-Universitaria di Modena, Italy.