Label-free blood serum detection by using surface-enhanced Raman spectroscopy and support vector machine for the preoperative diagnosis of parotid gland tumors.

Journal: BMC cancer
Published Date: Oct 5, 2015

Abstract

BACKGROUND: It is difficult for the parotid gland neoplasms to make an accurate preoperative diagnosis due to the restriction of biopsy in the parotid gland neoplasms. The aim of this study is to apply the surface-enhanced Raman spectroscopy (SERS) method for the blood serum biochemical detection and use the support vector machine for the analysis in order to develop a simple but accurate blood serum detection for preoperative diagnosis of the parotid gland neoplasms.

Authors

  • Bing Yan
    Department of Otolaryngology Head and Neck Surgery, the First Affiliated Hosipital of Xiamen University, Xiamen, China.
  • Bo Li
    Electric Power Research Institute, Yunnan Power Grid Co., Ltd., Kunming, Yunnan, China.
  • Zhining Wen
    College of Chemistry, Sichuan University, Chengdu, Sichuan, China.
  • Xianyang Luo
    Department of Otolaryngology Head and Neck Surgery, the First Affiliated Hosipital of Xiamen University, Xiamen, China.
  • Lili Xue
    Department of Stomatology, the First Affiliated Hosipital of Xiamen University, Xiamen, China.
  • Longjiang Li
    State Key Laboratory of Oral disease, Sichuan University, Chengdu, Sichuan, China. muzili63@163.com.

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