Supervised learning technique for the automated identification of white matter hyperintensities in traumatic brain injury.

Journal: Brain injury
Published Date: Jan 1, 2016

Abstract

BACKGROUND: White matter hyperintensities (WMHs) are foci of abnormal signal intensity in white matter regions seen with magnetic resonance imaging (MRI). WMHs are associated with normal ageing and have shown prognostic value in neurological conditions such as traumatic brain injury (TBI). The impracticality of manually quantifying these lesions limits their clinical utility and motivates the utilization of machine learning techniques for automated segmentation workflows.

Authors

  • James R Stone
    a Department of Radiology and Medical Imaging.
  • Elisabeth A Wilde
    c Michael E. DeBakey Veterans Affairs Medical Center , Houston , TX , USA.
  • Brian A Taylor
    c Michael E. DeBakey Veterans Affairs Medical Center , Houston , TX , USA.
  • David F Tate
    g Missouri Institute of Mental Health, University of Missouri , St. Louis , MO , USA.
  • Harvey Levin
    c Michael E. DeBakey Veterans Affairs Medical Center , Houston , TX , USA.
  • Erin D Bigler
    h Department of Psychology , Brigham Young University , Provo , UT , USA.
  • Randall S Scheibel
    c Michael E. DeBakey Veterans Affairs Medical Center , Houston , TX , USA.
  • Mary R Newsome
    c Michael E. DeBakey Veterans Affairs Medical Center , Houston , TX , USA.
  • Andrew R Mayer
    i Department of Translational Neuroscience , The Mind Research Network , Albuquerque , NM , USA.
  • Tracy Abildskov
    h Department of Psychology , Brigham Young University , Provo , UT , USA.
  • Garrett M Black
    d Department of Physical Medicine and Rehabilitation.
  • Michael J Lennon
    k Hunter Holmes McGuire Veterans Affairs Medical Center , Richmond , VA , USA.
  • Gerald E York
    l Alaska Radiology Associates , Anchorage , AK , USA.
  • Rajan Agarwal
    c Michael E. DeBakey Veterans Affairs Medical Center , Houston , TX , USA.
  • Jorge DeVillasante
    m Department of Radiology , USF Morsani College of Medicine , Tampa , FL , USA.
  • John L Ritter
    n Department of Radiology , San Antonio Military Medical Center , San Antonio , TX , USA.
  • Peter B Walker
    p Naval Medical Research Center , Silver Spring, MD , USA.
  • Stephen T Ahlers
    p Naval Medical Research Center , Silver Spring, MD , USA.
  • Nicholas J Tustison
    a Department of Radiology and Medical Imaging.

Keywords

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