AIMC Topic: Brain Injuries, Traumatic

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Deep Learning-Based Classification of Temporal Stages of AT8-Labeled Tau Pathology After Experimental Traumatic Brain Injury.

Neuroinformatics
Tauopathies are characterised by a progressive accumulation of hyperphosphorylated tau. However, early and intermediate stages remain challenging to quantify due to subtle and heterogeneous morphological characteristics. This study evaluates a deep l...

Prediction of Postoperative Venous Thromboembolism in Patients With Traumatic Brain Injury: Model Development and Validation Study.

JMIR medical informatics
BACKGROUND: Venous thromboembolism (VTE) remains a critical cause of mortality among patients who are hospitalized. Patients with traumatic brain injury (TBI) are particularly susceptible to VTE due to coagulation abnormalities and immobilization. De...

Piezo-Nanowired Stem Cells: Ultrasound-Powered Neuronal Commitment for Rapid Neural Circuit Reconstruction after Traumatic Brain Injury.

ACS nano
The inherently constrained regenerative capacity of neuronal tissue poses a major obstacle to repairing traumatic brain injury. While neural stem cell transplantation holds promise, its efficacy is constrained by slow and inefficient neuronal differe...

Multifactorial Biomarkers for "Talk and Deteriorate" after Head Trauma Identified Using Machine Learning.

Neurologia medico-chirurgica
Talk and Deteriorate refers to a clinical course where a patient is able to speak immediately after a traumatic brain injury but subsequently deteriorates in consciousness. Talk and Deteriorate outcomes are poor, and reliable prediction may help impr...

Machine Learning Models to Predict Withdrawal of Life-Sustaining Therapy in Patients With Severe Traumatic Brain Injury.

Neurology
BACKGROUND AND OBJECTIVES: Over half of all deaths after traumatic brain injury (TBI) follow the decision to withdraw life-sustaining therapy (WLST). Despite recent improvements in TBI mortality, rates of WLST have remained unchanged, potentially ref...

Progesterone for Traumatic Brain Injury, Experimental Clinical Treatment III Trial Revisited: Objective Classification of Traumatic Brain Injury With Brain Imaging Segmentation and Biomarker Levels.

Critical care explorations
OBJECTIVE: This post hoc study of the Progesterone for Traumatic Brain Injury, Experimental Clinical Treatment (ProTECT) III trial investigates whether improving traumatic brain injury (TBI) classification, using serum biomarkers (glial fibrillary ac...

Robot-assisted gait training after severe traumatic brain injury for walking ability and social participation: protocol for a feasibility study.

BMJ open
INTRODUCTION: Traumatic brain injury (TBI) is a traumatic head injury that can lead to gait-related disabilities, and exoskeleton training may be beneficial for the recovery of this function in these patients. The objective of this study is to determ...

Identifying key physiological and clinical factors for traumatic brain injury patient management using network analysis and machine learning.

PloS one
In the intensive care unit (ICU), managing traumatic brain injury (TBI) patients presents significant challenges due to the dynamic interaction between physiological and clinical markers. This study aims to uncover these subtle interconnections and i...

A practical approach to predicting long-term outcomes in traumatic brain injury: Enhancing clinical decision-making with machine learning.

Computers in biology and medicine
BACKGROUND: Traumatic brain injury (TBI) is among the most prevalent causes of emergency department visits globally. TBI leads to high morbidity and mortality rates, which poses a noteworthy burden on the medical system regarding both patients and ec...

Optimizing Vital Signs in Patients With Traumatic Brain Injury: Reinforcement Learning Algorithm Development and Validation.

Journal of medical Internet research
BACKGROUND: Traumatic brain injury (TBI) is a critically ill disease with a high mortality rate, and clinical treatment is committed to continuously optimizing treatment strategies to improve survival rates.