AIMC Topic: Brain Injuries, Traumatic

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Multimodal nomogram integrating deep learning radiomics and hemodynamic parameters for early prediction of post-craniotomy intracranial hypertension.

Scientific reports
To evaluate the effectiveness of deep learning radiomics nomogram in distinguishing early intracranial hypertension (IH) following primary decompressive craniectomy (DC) in patients with severe traumatic brain injury (TBI) and to demonstrate its pote...

Uncovering injury-specific proteomic signatures and neurodegenerative risks in single and repetitive traumatic brain injury.

Signal transduction and targeted therapy
Traumatic brain injury (TBI) is a major public health concern associated with an increased risk of neurodegenerative diseases including Alzheimer's disease (AD), Parkinson's disease (PD), and chronic traumatic encephalopathy, yet the underlying molec...

Eyes Are the Windows to the Soul: Reviewing the Possible Use of the Retina to Indicate Traumatic Brain Injury.

International journal of molecular sciences
Traumatic brain injury (TBI) induces complex molecular and cellular responses, often leading to vision deterioration and potential mortality. Current objective diagnostic methods are limited, necessitating the development of novel tools to assess dis...

The Role of Hydrogen Sulfide in the Localization and Structural-Functional Organization of p53 Following Traumatic Brain Injury: Development of a YOLO Model for Detection and Quantification of Apoptotic Nuclei.

International journal of molecular sciences
Traumatic brain injury (TBI) triggers a cascade of molecular and cellular disturbances, including apoptosis, inflammation, and destabilization of neuronal connections. The transcription factor p53 plays a pivotal role in regulating cell fate followin...

Semantic-consistent diffusion model for unsupervised traumatic brain injury detection and segmentation from computed tomography images.

Medical physics
BACKGROUND: Unsupervised traumatic brain injury (TBI) lesion detection aims to identify and segment abnormal regions, such as cerebral edema and hemorrhages, using only healthy training data. Recent advancements in generative models have achieved suc...

Is artificial intelligence superior to traditional regression methods in predicting prognosis of adult traumatic brain injury?

Neurosurgical review
Traumatic brain injury (TBI) is a significant global health issue with high morbidity and mortality rates. Recent studies have shown that machine learning algorithms outperform traditional logistic regression models in predicting functional outcomes ...

Enhanced prediction of ventilator-associated pneumonia in patients with traumatic brain injury using advanced machine learning techniques.

Scientific reports
Ventilator-associated pneumonia significantly increases morbidity, mortality, and healthcare costs among patients with traumatic brain injury. Accurately predicting risk can facilitate earlier interventions and improve patient outcomes. This study le...

Machine Learning Approaches to Prognostication in Traumatic Brain Injury.

Current neurology and neuroscience reports
PURPOSE OF REVIEW: This review investigates the use of machine learning (ML) in prognosticating outcomes for traumatic brain injury (TBI). It underscores the benefits of ML models in processing and integrating complex, multimodal data-including clini...

Developing practical machine learning survival models to identify high-risk patients for in-hospital mortality following traumatic brain injury.

Scientific reports
Machine learning (ML) offers precise predictions and could improve patient care, potentially replacing traditional scoring systems. A retrospective study at Emtiaz Hospital analyzed 3,180 traumatic brain injury (TBI) patients. Nineteen variables were...

Development of clinical decision support for patients older than 65 years with fall-related TBI using artificial intelligence modeling.

PloS one
BACKGROUND: Older persons comprise most traumatic brain injury (TBI)-related hospitalizations and deaths and are particularly susceptible to fall-induced TBIs. The combination of increased frailty and susceptibility to clinical decline creates a sign...