Dynamic cerebral reorganization in the pathophysiology of schizophrenia: a MRI-derived cortical thickness study.

Journal: Psychological medicine

Published Date: May 26, 2016

Abstract

BACKGROUND: A structural neuroanatomical change indicating a reduction in brain tissue is a notable feature of schizophrenia. Several pathophysiological processes such as aberrant cortical maturation, progressive tissue loss and compensatory tissue increase could contribute to the structural changes seen in schizophrenia.

Authors

S Guo

Key Laboratory of High Performance Computing and Stochastic Information Processing (Ministry of Education of China),College of Mathematics and Computer Science,Hunan Normal University,Changsha,People's Republic of China.
L Palaniyappan

Division of Psychiatry & Applied Psychology,Centre for Translational Neuroimaging in Mental Health,Institute of Mental Health,University of Nottingham,Nottingham,UK.
P F Liddle

Division of Psychiatry & Applied Psychology,Centre for Translational Neuroimaging in Mental Health,Institute of Mental Health,University of Nottingham,Nottingham,UK.
J Feng

Department of Computer Science,University of Warwick,Coventry,UK.

Keywords

Adult Cerebral Cortex Disease Progression Female Humans Magnetic Resonance Imaging Male Neuronal Plasticity Schizophrenia Sensitivity and Specificity Support Vector Machine Time Factors Young Adult

External Resources

View on PubMed Access via DOI PubMed (27228263)

Dynamic cerebral reorganization in the pathophysiology of schizophrenia: a MRI-derived cortical thickness study.

Abstract

Authors

Keywords

External Resources

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