A prediction model for early death in non-small cell lung cancer patients following curative-intent chemoradiotherapy.

Journal: Acta oncologica (Stockholm, Sweden)
Published Date: Feb 1, 2018

Abstract

BACKGROUND: Early death after a treatment can be seen as a therapeutic failure. Accurate prediction of patients at risk for early mortality is crucial to avoid unnecessary harm and reducing costs. The goal of our work is two-fold: first, to evaluate the performance of a previously published model for early death in our cohorts. Second, to develop a prognostic model for early death prediction following radiotherapy.

Authors

  • Arthur Jochems
    a Department of Radiation Oncology (MAASTRO), GROW - School for Oncology and Developmental Biology , Maastricht University Medical Centre , Maastricht , The Netherlands.
  • Issam El-Naqa
    b Department of Radiation Oncology , University of Michigan , Ann Arbor , MI , USA.
  • Marc Kessler
    b Department of Radiation Oncology , University of Michigan , Ann Arbor , MI , USA.
  • Charles S Mayo
    b Department of Radiation Oncology , University of Michigan , Ann Arbor , MI , USA.
  • Shruti Jolly
    b Department of Radiation Oncology , University of Michigan , Ann Arbor , MI , USA.
  • Martha Matuszak
    b Department of Radiation Oncology , University of Michigan , Ann Arbor , MI , USA.
  • Corinne Faivre-Finn
    c The University of Manchester, Manchester Academic Health Science Centre, The Christie NHS Foundation Trust , Manchester , UK.
  • Gareth Price
    c The University of Manchester, Manchester Academic Health Science Centre, The Christie NHS Foundation Trust , Manchester , UK.
  • Lois Holloway
    d Cancer Therapy Centre, Liverpool Hospital , Liverpool , NSW , Australia.
  • Shalini Vinod
    d Cancer Therapy Centre, Liverpool Hospital , Liverpool , NSW , Australia.
  • Matthew Field
    d Cancer Therapy Centre, Liverpool Hospital , Liverpool , NSW , Australia.
  • Mohamed Samir Barakat
    d Cancer Therapy Centre, Liverpool Hospital , Liverpool , NSW , Australia.
  • David Thwaites
    e Institute of Medical Physics, School of Physics , University of Sydney , Sydney , NSW , Australia.
  • Dirk de Ruysscher
    a Department of Radiation Oncology (MAASTRO), GROW - School for Oncology and Developmental Biology , Maastricht University Medical Centre , Maastricht , The Netherlands.
  • Andre Dekker
    Department of Radiation Oncology (MAASTRO Clinic), Dr. Tanslaan 12, Maastricht, The Netherlands.
  • Philippe Lambin
    Department of Radiation Oncology (MAASTRO Clinic), Dr. Tanslaan 12, Maastricht, The Netherlands.

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