Gene Ontology-based function prediction of long non-coding RNAs using bi-random walk.

Journal: BMC medical genomics
Published Date: Nov 20, 2018

Abstract

BACKGROUND: With the development of sequencing technology, more and more long non-coding RNAs (lncRNAs) have been identified. Some lncRNAs have been confirmed that they play an important role in the process of development through the dosage compensation effect, epigenetic regulation, cell differentiation regulation and other aspects. However, the majority of the lncRNAs have not been functionally characterized. Explore the function of lncRNAs and the regulatory network has become a hot research topic currently.

Authors

  • Jingpu Zhang
    School of Computer and Data Science, Henan University of Urban Construction, Pingdingshan, 467000, China.
  • Shuai Zou
    School of Information Science and Engineering, Central South University, Changsha, 410083, China.
  • Lei Deng
    1] Center for Brain Inspired Computing Research (CBICR), Department of Precision Instrument, Tsinghua University, Beijing 100084, China [2] Optical Memory National Engineering Research Center, Department of Precision Instrument, Tsinghua University, Beijing 100084, China.

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