Predicting chemo-brain in breast cancer survivors using multiple MRI features and machine-learning.

Journal: Magnetic resonance in medicine
PMID: 30417933

Abstract

PURPOSE: Breast cancer (BC) is the most common cancer in women worldwide. There exist various advanced chemotherapy drugs for BC; however, chemotherapy drugs may result in brain damage during treatment. When a patient's brain is changed in response to chemo drugs, it is termed chemo-brain. In this study, we aimed to construct machine-learning models to detect the subtle alternations of the brain in postchemotherapy BC patients.

Authors

  • Vincent Chin-Hung Chen
    School of Medicine, Chang Gung University, Taoyuan, Taiwan; Department of Psychiatry, Chang Gung Memorial Hospital, Chiayi, Taiwan.
  • Tung-Yeh Lin
    Department of Medical Imaging and Radiological Sciences, Chang Gung University, Taoyuan, Taiwan.
  • Dah-Cherng Yeh
    Breast Medical Center, Cheng Ching Hospital Chung Kang Branch, Taichung, Taiwan.
  • Jyh-Wen Chai
    Department of Radiology, Taichung Veterans General Hospital, Taichung, Taiwan.
  • Jun-Cheng Weng
    Department of Psychiatry, Chang Gung Memorial Hospital, Chiayi, Taiwan.

Keywords

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