A combined analysis of TyG index, SII index, and SIRI index: positive association with CHD risk and coronary atherosclerosis severity in patients with NAFLD.

Journal: Frontiers in endocrinology
PMID: 38260163

Abstract

BACKGROUND: Insulin resistance(IR) and inflammation have been regarded as common potential mechanisms in coronary heart disease (CHD) and non-alcoholic fatty liver disease (NAFLD). Triglyceride-glucose (TyG) index is a novel biomarker of insulin resistance, System immune-inflammation index(SII) and Systemic inflammation response index(SIRI) are novel biomarkers of inflammation, these biomarkers have not been studied in CHD with NAFLD patients. This study investigated the correlation between the TyG index, SII index, and SIRI index and CHD risk among NAFLD patients.

Authors

  • Wenyuan Dong
    Vasculocardiology Department, The Third People's Hospital of Datong, Datong, Shanxi, China.
  • Yuxin Gong
    Key Laboratory of Cardiovascular Diseases, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
  • Jianqi Zhao
    Vasculocardiology Department, The First People's Hospital of Jinzhong, Jinzhong, Shanxi, China.
  • Yanan Wang
    Vasculocardiology Department, The Third People's Hospital of Datong, Datong, Shanxi, China.
  • Bao Li
    Key Laboratory of Cardiovascular Diseases, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
  • Youdong Yang
    Vasculocardiology Department, The Third People's Hospital of Datong, Datong, Shanxi, China.

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