Machine Learning: Advanced Image Segmentation Using ilastik.

Journal: Methods in molecular biology (Clifton, N.J.)
Published Date:

Abstract

Segmentation is one of the most ubiquitous problems in biological image analysis. Here we present a machine learning-based solution to it as implemented in the open source ilastik toolkit. We give a broad description of the underlying theory and demonstrate two workflows: Pixel Classification and Autocontext. We illustrate their use on a challenging problem in electron microscopy image segmentation. After following this walk-through, we expect the readers to be able to apply the necessary steps to their own data and segment their images by either workflow.

Authors

  • Anna Kreshuk
    EMBL, Heidelberg, Germany.
  • Chong Zhang
    Department of Big Data Management and Application, School of International Economics and Management, Beijing Technology and Business University, Beijing 100048, China.