Achieving state-of-the-art performance with deep neural population dynamics models requires extensive hyperparameter tuning for each dataset. AutoLFADS is a model-tuning framework that automatically produces high-performing autoencoding models on dat...
The directionality of network information flow dictates how networks process information. A central component of information processing in both biological and artificial neural networks is their ability to perform synergistic integration-a type of co...
Investigations of spatial cellular composition of tissue architectures revealed by multiplexed in situ RNA detection often rely on inaccurate cell segmentation or prior biological knowledge from complementary single-cell sequencing experiments. Here,...
There is an unmet need to develop robust predictive algorithms to preoperatively identify pediatric epilepsy patients who will respond to vagus nerve stimulation (VNS). Given the similarity in the neural circuitry between vagus and median nerve affer...
OBJECTIVE: The extraction and identification of single-unit activities in intracortically recorded electric signals have a key role in basic neuroscience, but also in applied fields, like in the development of high-accuracy brain-computer interfaces....
Behavior is controlled by complex neural networks in which neurons process thousands of inputs. However, even short spike trains evoked in a single cortical neuron were demonstrated to be sufficient to influence behavior in vivo. Specifically, irregu...
Although many real-time neural decoding algorithms have been proposed for brain-machine interface (BMI) applications over the years, an optimal, consensual approach remains elusive. Recent advances in deep learning algorithms provide new opportunitie...
Visual scene category representations emerge very rapidly, yet the computational transformations that enable such invariant categorizations remain elusive. Deep convolutional neural networks (CNNs) perform visual categorization at near human-level ac...
The Journal of neuroscience : the official journal of the Society for Neuroscience
Jul 16, 2018
Measures of moment-to-moment fluctuations in brain activity of an individual at rest have been shown to be a sensitive and reliable metric for studying pathological brain mechanisms across various chronic pain patient populations. However, the relati...
Proceedings of the National Academy of Sciences of the United States of America
Apr 30, 2018
Neurons responding to different whiskers are spatially intermixed in the superficial layer 2/3 (L2/3) of the rodent barrel cortex, where a single whisker deflection activates a sparse, distributed neuronal population that spans multiple cortical colu...
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