AIMC Topic: Somatosensory Cortex

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A large-scale neural network training framework for generalized estimation of single-trial population dynamics.

Nature methods
Achieving state-of-the-art performance with deep neural population dynamics models requires extensive hyperparameter tuning for each dataset. AutoLFADS is a model-tuning framework that automatically produces high-performing autoencoding models on dat...

Partial information decomposition reveals that synergistic neural integration is greater downstream of recurrent information flow in organotypic cortical cultures.

PLoS computational biology
The directionality of network information flow dictates how networks process information. A central component of information processing in both biological and artificial neural networks is their ability to perform synergistic integration-a type of co...

Spage2vec: Unsupervised representation of localized spatial gene expression signatures.

The FEBS journal
Investigations of spatial cellular composition of tissue architectures revealed by multiplexed in situ RNA detection often rely on inaccurate cell segmentation or prior biological knowledge from complementary single-cell sequencing experiments. Here,...

Somatosensory evoked fields predict response to vagus nerve stimulation.

NeuroImage. Clinical
There is an unmet need to develop robust predictive algorithms to preoperatively identify pediatric epilepsy patients who will respond to vagus nerve stimulation (VNS). Given the similarity in the neural circuitry between vagus and median nerve affer...

Spike detection and sorting with deep learning.

Journal of neural engineering
OBJECTIVE: The extraction and identification of single-unit activities in intracortically recorded electric signals have a key role in basic neuroscience, but also in applied fields, like in the development of high-accuracy brain-computer interfaces....

Sensitivity to Stimulus Irregularity Is Inherent in Neural Networks.

Neural computation
Behavior is controlled by complex neural networks in which neurons process thousands of inputs. However, even short spike trains evoked in a single cortical neuron were demonstrated to be sufficient to influence behavior in vivo. Specifically, irregu...

Decoding Movements from Cortical Ensemble Activity Using a Long Short-Term Memory Recurrent Network.

Neural computation
Although many real-time neural decoding algorithms have been proposed for brain-machine interface (BMI) applications over the years, an optimal, consensual approach remains elusive. Recent advances in deep learning algorithms provide new opportunitie...

Shared spatiotemporal category representations in biological and artificial deep neural networks.

PLoS computational biology
Visual scene category representations emerge very rapidly, yet the computational transformations that enable such invariant categorizations remain elusive. Deep convolutional neural networks (CNNs) perform visual categorization at near human-level ac...

Abnormal Low-Frequency Oscillations Reflect Trait-Like Pain Ratings in Chronic Pain Patients Revealed through a Machine Learning Approach.

The Journal of neuroscience : the official journal of the Society for Neuroscience
Measures of moment-to-moment fluctuations in brain activity of an individual at rest have been shown to be a sensitive and reliable metric for studying pathological brain mechanisms across various chronic pain patient populations. However, the relati...

Structured networks support sparse traveling waves in rodent somatosensory cortex.

Proceedings of the National Academy of Sciences of the United States of America
Neurons responding to different whiskers are spatially intermixed in the superficial layer 2/3 (L2/3) of the rodent barrel cortex, where a single whisker deflection activates a sparse, distributed neuronal population that spans multiple cortical colu...