Impact of Machine Learning With Multiparametric Magnetic Resonance Imaging of the Breast for Early Prediction of Response to Neoadjuvant Chemotherapy and Survival Outcomes in Breast Cancer Patients.

Journal: Investigative radiology
Published Date:

Abstract

PURPOSE: The aim of this study was to assess the potential of machine learning with multiparametric magnetic resonance imaging (mpMRI) for the early prediction of pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) and of survival outcomes in breast cancer patients.

Authors

  • Amirhessam Tahmassebi
    Department of Scientific Computing, Florida State University, Tallahassee, Florida 32306-4120, United States of America.
  • Georg J Wengert
    Division of Molecular and Gender Imaging, Department of Biomedical Imaging and Image-Guided Therapy.
  • Thomas H Helbich
    Division of Molecular and Gender Imaging, Department of Biomedical Imaging and Image-Guided Therapy.
  • Zsuzsanna Bago-Horvath
    Department of Pathology.
  • Sousan Alaei
    Department of Pathology.
  • Rupert Bartsch
    Division of Oncology, Department of Internal Medicine, and.
  • Peter Dubsky
    Department of Surgery, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
  • Pascal Baltzer
    Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna General Hospital, Vienna, Austria. Electronic address: pascal.baltzer@meduniwien.ac.at.
  • Paola Clauser
    Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna General Hospital, Vienna, Austria.
  • Panagiotis Kapetas
    Division of Molecular and Gender Imaging, Department of Biomedical Imaging and Image-Guided Therapy.
  • Elizabeth A Morris
    Department of Radiology, Breast Imaging Service, Memorial Sloan Kettering Cancer Center, New York, NY.
  • Anke Meyer-Baese
    2 Department of Scientific Computing, Florida State University, Tallahassee, FL, USA.
  • Katja Pinker
    Department of Radiology, Columbia University, Vagelos College of Physicians and Surgeons, New York, New York, USA.