Smooth Bayesian network model for the prediction of future high-cost patients with COPD.

Journal: International journal of medical informatics
Published Date:

Abstract

INTRODUCTION: The clinical course of chronic obstructive pulmonary disease (COPD) is marked by acute exacerbation events that increase hospitalization rates and healthcare spending. The early identification of future high-cost patients with COPD may decrease healthcare spending by informing individualized interventions that prevent exacerbation events and decelerate disease progression. Existing studies of cost prediction of other chronic diseases have applied regression and machine-learning methods that cannot capture the complex causal relationships between COPD factors. Thus, the exploration of these factors through nonlinear, high-dimensional but explainable modeling is greatly needed.

Authors

  • Shaochong Lin
    Department of Management Sciences, City University of Hong Kong, Hong Kong.
  • Qingpeng Zhang
    Department of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong, Hong Kong SAR, China.
  • Frank Chen
    Department of Radiology, University of Southern California, Los Angeles, CA, USA.
  • Li Luo
    Department of Intensive Care Unit, First Affiliated Hospital, Chongqing Medical University, Chongqing 400016, China.
  • Lei Chen
    Department of Chemistry, Stony Brook University Stony Brook NY USA.
  • Wei Zhang
    The First Affiliated Hospital of Nanchang University, Nanchang, China.