Simulating Dual-Energy X-Ray Absorptiometry in CT Using Deep-Learning Segmentation Cascade.

Journal: Journal of the American College of Radiology : JACR
Published Date:

Abstract

PURPOSE: Osteoporosis is an underdiagnosed condition despite effective screening modalities. Dual-energy x-ray absorptiometry (DEXA) screening, although recommended in clinical guidelines, remains markedly underutilized. In contrast to DEXA, CT utilization is high and presents a valuable data source for opportunistic osteoporosis screening. The purpose of this study was to describe a method to simulate lumbar DEXA scores from routinely acquired CT studies using a machine-learning algorithm.

Authors

  • Arun Krishnaraj
    Department of Radiology and Medical Imaging, University of Virginia, Charlottesville, Virginia. Electronic address: arunk@virginia.edu.
  • Spencer Barrett
    Department of Radiology and Medical Imaging, University of Virginia, Charlottesville, Virginia.
  • Orna Bregman-Amitai
    Zebra Medical Vision, Shfayim, Israel.
  • Michael Cohen-Sfady
    Zebra Medical Vision, Shfayim, Israel.
  • Amir Bar
    Zebra Medical Vision, Shfayim, Israel.
  • David Chettrit
    Zebra Medical Vision, Shfayim, Israel.
  • Mila Orlovsky
    Zebra Medical Vision, Shfayim, Israel.
  • Eldad Elnekave
    Zebra Medical Vision LTD, Shfayim, Israel. Eldad@zebra-med.com.