Diagnostic value of spirometry vs impulse oscillometry: A comparative study in children with sickle cell disease.

Journal: Pediatric pulmonology
PMID: 31211524

Abstract

BACKGROUND: Spirometry is conventionally used to diagnose airway diseases in children with sickle cell disease (C-SCD). However, spirometry is difficult for younger children to perform, is effort dependent, and it provides limited information on respiratory mechanics. Impulse oscillometry (IOS) is an effort-independent pulmonary function test (PFT), which measures total airway resistance (R5Hz) and reactance (AX). IOS could be advantageous without certain limitations of spirometry.

Authors

  • Pritish Mondal
    Division of Pediatric Pulmonology, Department of Pediatrics, Penn State College of Medicine, Hershey, Pennsylvania.
  • Alison Yirinec
    Department of Pediatrics, Penn State College of Medicine, Hershey, Pennsylvania.
  • Vishal Midya
    Department of Biostatistics and Bioinformatics, Penn State College of Medicine, Hershey, Pennsylvania.
  • Binu-John Sankoorikal
    Division of Pediatric Pulmonology, Department of Pediatrics, Penn State College of Medicine, Hershey, Pennsylvania.
  • Gayle Smink
    Division of Pediatric Hematology, Department of Pediatrics, Penn State College of Medicine, Hershey, Pennsylvania.
  • Arshjot Khokhar
    Department of Pediatrics, Penn State College of Medicine, Hershey, Pennsylvania.
  • Mutasim Abu-Hasan
    Division of Pediatric Pulmonology, Department of Pediatrics, University of Florida, Gainesville, Florida.
  • Rebecca Bascom
    Division of Pulmonology and Critical Care, Department of Medicines, Penn State College of Medicine, Hershey, Pennsylvania.

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