A semantic database for integrated management of image and dosimetric data in low radiation dose research in medical imaging.

Journal: AMIA ... Annual Symposium proceedings. AMIA Symposium
PMID:

Abstract

Medical ionizing radiation procedures and especially medical imaging are a non negligible source of exposure to patients. Whereas the biological effects of high absorbed doses are relatively well known, the effects of low absorbed doses are still debated. This work presents the development of a computer platform called Image and Radiation Dose BioBank (IRDBB) to manage research data produced in the context of the MEDIRAD project, a European project focusing on research on low doses in the context of medical procedures. More precisely, the paper describes a semantic database linking dosimetric data (such as absorbed doses to organs) to the images corresponding to X-rays exposure (such as CT images) or scintigraphic images (such as SPECT or PET images) that allow measuring the distribution of a radiopharmaceutical. The main contributions of this work are: 1) the implementation of the semantic database of the IRDBB system and 2) an ontology called OntoMEDIRAD covering the domain of discourse involved in MEDIRAD research data, especially many concepts from the DICOM standard modelled according to a realist approach.

Authors

  • Bernard Gibaud
    Inserm, LTSI - UMR_S 1099, Univ Rennes, Rennes, France. bernard.gibaud@univ-rennes1.fr.
  • Marine Brenet
    Univ Rennes, Inserm, LTSI UMR 1099, Rennes, France.
  • Guillaume Pasquier
    B-COM Institute of Research and Technology, Rennes, France.
  • Alex Vergara Gil
    Centre Recherche en Cancérologie de Toulouse, Toulouse, France.
  • Manuel Bardiès
    Centre Recherche en Cancérologie de Toulouse, Toulouse, France.
  • John Stratakis
    Medical Physics Department, School of Medicine, University of Crete, Heraklion, Greece.
  • John Damilakis
    Department of Medical Physics, Faculty of Medicine, University of Crete, Greece.
  • Nicolas Van Dooren
    Institute of Translational Molecular Imaging, Genève.
  • Joël Spaltenstein
    Institute of Translational Molecular Imaging, Genève.
  • Osman Ratib
    Institute of Translational Molecular Imaging, Genève.