Development and Validation of a Machine Learning Individualized Treatment Rule in First-Episode Schizophrenia.

Journal: JAMA network open

Published Date: Feb 5, 2020

IMPORTANCE: Little guidance exists to date on how to select antipsychotic medications for patients with first-episode schizophrenia.

Chi-Shin Wu

Department of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan R.O.C.
Alex R Luedtke

Department of Statistics, University of Washington, Seattle.
Ekaterina Sadikova

Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts.
Hui-Ju Tsai

Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan.
Shih-Cheng Liao

Department of Psychiatry, National Taiwan University Hospital & College of Medicine, National Taiwan University, Taipei City, Taiwan.
Chen-Chung Liu

Department of Psychiatry, National Taiwan University Hospital & College of Medicine, National Taiwan University, Taipei City, Taiwan.
Susan Shur-Fen Gau

Department of Psychiatry, National Taiwan University Hospital & College of Medicine, National Taiwan University, Taipei City, Taiwan.
Tyler J VanderWeele

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Ronald C Kessler

Department of Health Care Policy, Harvard Medical School.

Adult Antipsychotic Agents Clinical Decision Rules Female Humans Machine Learning Male Middle Aged Models, Statistical Precision Medicine Prognosis Retrospective Studies Schizophrenia Treatment Outcome Young Adult

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