Automatization and improvement of μCT analysis for murine lung disease models using a deep learning approach.
Journal:
Respiratory research
Published Date:
May 24, 2020
Abstract
BACKGROUND: One of the main diagnostic tools for lung diseases in humans is computed tomography (CT). A miniaturized version, micro-CT (μCT) is utilized to examine small rodents including mice. However, fully automated threshold-based segmentation and subsequent quantification of severely damaged lungs requires visual inspection and manual correction.