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X-Ray Microtomography

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A modular cage may prevent endplate damage and improve spinal deformity correction.

Clinical biomechanics (Bristol, Avon)
BACKGROUND: Anterior lumbar interbody fusion is performed to fuse pathological spinal segments, generally, with a monobloc cage inserted by impact forces. Recently developed three-part modular cages attempt to reduce the impact forces, minimize the d...

Identification of Root Canal Morphology in Fused-rooted Mandibular Second Molars From X-ray Images Based on Deep Learning.

Journal of endodontics
INTRODUCTION: Understanding the intricate anatomical morphology of fused-rooted mandibular second molars (MSMs) is essential for root canal treatment. The present study utilized a deep learning approach to identify the three-dimensional root canal mo...

Characterization and quantification of in-vitro equine bone resorption in 3D using μCT and deep learning-aided feature segmentation.

Bone
High cyclic strains induce formation of microcracks in bone, triggering targeted bone remodeling, which entails osteoclastic resorption. Racehorse bone is an ideal model for studying the effects of high-intensity loading, as it is subject to focal fo...

A Multimodal Transfer Learning Approach for Histopathology and SR-microCT Low-Data Regimes Image Segmentation.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Osteocyte-lacunar bone structures are a discerning marker for bone pathophysiology, given their geometric alterations observed during aging and diseases. Deep Learning (DL) image analysis has showcased the potential to comprehend bone health associat...

Self-adaptive deep learning-based segmentation for universal and functional clinical and preclinical CT image analysis.

Computers in biology and medicine
BACKGROUND: Methods to monitor cardiac functioning non-invasively can accelerate preclinical and clinical research into novel treatment options for heart failure. However, manual image analysis of cardiac substructures is resource-intensive and error...

Cell quantification at the osteochondral interface from synchrotron radiation phase contrast micro-computed tomography images using a deep learning approach.

Scientific reports
Osteochondral interface consists of two tissues: the calcified cartilage (CC) containing chondrocytes, and subchondral bone (SCB) containing osteocytes that interact with each other. In this study, we propose a new method for the three-dimensional (3...

Reconstructing 3D histological structures using machine learning (artificial intelligence) algorithms.

Pathologie (Heidelberg, Germany)
BACKGROUND: Histomorphometry is currently the gold standard for bone microarchitectural examinations. This relies on two-dimensional (2D) sections to deduce the spatial properties of structures. Micromorphometric parameters are calculated from these ...

Assessing the cardioprotective effects of exercise in APOE mouse models using deep learning and photon-counting micro-CT.

PloS one
BACKGROUND: The allelic variations of the apolipoprotein E (APOE) gene play a critical role in regulating lipid metabolism and significantly impact cardiovascular disease risk (CVD). This study aimed to evaluate the impact of exercise on cardiac stru...

A robust deep learning approach for segmenting cortical and trabecular bone from 3D high resolution µCT scans of mouse bone.

Scientific reports
Recent advancements in deep learning have significantly enhanced the segmentation of high-resolution microcomputed tomography (µCT) bone scans. In this paper, we present the dual-branch attention-based hybrid network (DBAHNet), a deep learning archit...

Enhancing synchrotron radiation micro-CT images using deep learning: an application of Noise2Inverse on bone imaging.

Journal of synchrotron radiation
In bone-imaging research, in situ synchrotron radiation micro-computed tomography (SRµCT) mechanical tests are used to investigate the mechanical properties of bone in relation to its microstructure. Low-dose computed tomography (CT) is used to prese...