Deep learning-based synthetic CT generation for paediatric brain MR-only photon and proton radiotherapy.

Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Published Date: Sep 23, 2020

Abstract

BACKGROUND AND PURPOSE: To enable accurate magnetic resonance imaging (MRI)-based dose calculations, synthetic computed tomography (sCT) images need to be generated. We aim at assessing the feasibility of dose calculations from MRI acquired with a heterogeneous set of imaging protocol for paediatric patients affected by brain tumours.

Authors

  • Matteo Maspero
    Department of Radiation Oncology, Imaging and Cancer Division, University Medical Center Utrecht, Utrecht, The Netherlands; Computational Imaging Group for MR Diagnostics & Therapy, Center for Image Sciences, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Laura G Bentvelzen
    Department of Radiotherapy, Division of Imaging & Oncology, University Medical Center Utrecht, , The Netherlands; Computational Imaging Group for MR diagnostics & therapy, Center for Image Sciences, University Medical Center Utrecht, , The Netherlands.
  • Mark H F Savenije
    Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Filipa Guerreiro
    Department of Radiotherapy, Division of Imaging & Oncology, University Medical Center Utrecht, , The Netherlands.
  • Enrica Seravalli
    Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Geert O Janssens
    Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands; Department of Radiation Oncology, Imaging and Cancer Division, University Medical Center Utrecht, Utrecht, The Netherlands. Electronic address: g.o.r.janssens@umcutrecht.nl.
  • Cornelis A T van den Berg
    Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Marielle E P Philippens
    Department of Radiotherapy, Division of Imaging & Oncology, University Medical Center Utrecht, Utrecht, The Netherlands.

Keywords

External Resources

Popular Topics
Recent Journals