Evaluation of the Classification Accuracy of the Kidney Biopsy Direct Immunofluorescence through Convolutional Neural Networks.

Journal: Clinical journal of the American Society of Nephrology : CJASN
PMID: 32938617

Abstract

BACKGROUND AND OBJECTIVES: Immunohistopathology is an essential technique in the diagnostic workflow of a kidney biopsy. Deep learning is an effective tool in the elaboration of medical imaging. We wanted to evaluate the role of a convolutional neural network as a support tool for kidney immunofluorescence reporting.

Authors

  • Giulia Ligabue
    Department of Surgery, Medicine, Dental Medicine and Morphological Sciences, University of Modena and Reggio Emilia, Modena, Italy.
  • Federico Pollastri
    Department of Engineering "Enzo Ferrari," University of Modena and Reggio Emilia, Modena, Italy.
  • Francesco Fontana
    Division of Nephrology, Dialysis and Renal Transplantation, Azienda Ospedaliera Universitaria Policlinico di Modena, Modena, Italy.
  • Marco Leonelli
    Division of Nephrology, Dialysis and Renal Transplantation, Azienda Ospedaliera Universitaria Policlinico di Modena, Modena, Italy.
  • Luciana Furci
    Division of Nephrology, Dialysis and Renal Transplantation, Azienda Ospedaliera Universitaria Policlinico di Modena, Modena, Italy.
  • Silvia Giovanella
    Department of Surgery, Medicine, Dental Medicine and Morphological Sciences, University of Modena and Reggio Emilia, Modena, Italy.
  • Gaetano Alfano
    Division of Nephrology, Dialysis and Renal Transplantation, Azienda Ospedaliera Universitaria Policlinico di Modena, Modena, Italy.
  • Gianni Cappelli
    Department of Surgery, Medicine, Dental Medicine and Morphological Sciences, University of Modena and Reggio Emilia, Modena, Italy.
  • Francesca Testa
    Division of Nephrology, Dialysis and Renal Transplantation, Azienda Ospedaliera Universitaria Policlinico di Modena, Modena, Italy.
  • Federico Bolelli
    Department of Engineering "Enzo Ferrari," University of Modena and Reggio Emilia, Modena, Italy.
  • Costantino Grana
    Department of Engineering "Enzo Ferrari," University of Modena and Reggio Emilia, Modena, Italy.
  • Riccardo Magistroni
    Department of Surgery, Medicine, Dental Medicine and Morphological Sciences, University of Modena and Reggio Emilia, Modena, Italy.

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