BACKGROUND: Differentiating between nontuberculous mycobacterial lung disease (NTM-LD) and pulmonary NTM colonization (NTM-Col) is difficult. Compared with healthy controls, patients with NTM-LD generally present immune tolerance along with increased...
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society
32009627
Recreational winter swimming in cold sea water evokes body responses to regularly repeated cold water immersion. However, the understanding of adaptive changes is still limited and data regarding very short-term exposure to severe cold stress are sca...
BACKGROUND: Oral mucosal lesions are widespread globally, have a high prevalence in clinical practice, and significantly impact patients' quality of life. However, their pathogenesis remains unclear. Recent evidences suggested that hematological para...
Multiple myeloma (MM) is a highly heterogeneous disease of malignant plasma cells. Diagnosis and monitoring of MM patients is based on bone marrow biopsies and detection of abnormal immunoglobulin in serum and/or urine. However, biopsies have a singl...
Clinical journal of the American Society of Nephrology : CJASN
32938617
BACKGROUND AND OBJECTIVES: Immunohistopathology is an essential technique in the diagnostic workflow of a kidney biopsy. Deep learning is an effective tool in the elaboration of medical imaging. We wanted to evaluate the role of a convolutional neura...
Toxoplasmosis is a zoonotic illness caused by . Those with a normal immune system normally recover without treatment. Immunocompromised individuals and pregnant women must be treated regularly. Toxoplasmosis is a serious illness that may reactivate i...
Computational intelligence and neuroscience
36744119
. Immunoglobulin proteins (IGP) (also called antibodies) are glycoproteins that act as B-cell receptors against external or internal antigens like viruses and bacteria. IGPs play a significant role in diverse cellular processes ranging from adhesion ...
BACKGROUND: Managing Canada's immunoglobulin (Ig) product resource allocation is challenging due to increasing demand, high expenditure, and global shortages. Detection of groups with high utilization rates can help with resource planning for Ig prod...
Cells detect changes in their external environments or communicate with each other through proteins on their surfaces. These cell surface proteins form a complicated network of interactions in order to fulfill their functions. The interactions betwee...
High throughput sequencing of B cell receptors (BCRs) is increasingly applied to study the immense diversity of antibodies. Learning biologically meaningful embeddings of BCR sequences is beneficial for predictive modeling. Several embedding methods ...