AIMC Topic: Immunoglobulins

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Prediction of interactions between cell surface proteins by machine learning.

Proteins Dec 5, 2023
Cells detect changes in their external environments or communicate with each other through proteins on their surfaces. These cell surface proteins form a complicated network of interactions in order to fulfill their functions. The interactions betwee...
Membrane Proteins Amino Acid Sequence Immunoglobulins Ligands Humans Machine Learning
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An unsupervised learning approach to identify immunoglobulin utilization patterns using electronic health records.

Transfusion Oct 20, 2023
BACKGROUND: Managing Canada's immunoglobulin (Ig) product resource allocation is challenging due to increasing demand, high expenditure, and global shortages. Detection of groups with high utilization rates can help with resource planning for Ig prod...
Electronic Health Records Adult Child, Preschool Inpatients Humans Unsupervised Machine Learning Immunoglobulins
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IGPred-HDnet: Prediction of Immunoglobulin Proteins Using Graphical Features and the Hierarchal Deep Learning-Based Approach.

Computational intelligence and neuroscience Jan 25, 2023
. Immunoglobulin proteins (IGP) (also called antibodies) are glycoproteins that act as B-cell receptors against external or internal antigens like viruses and bacteria. IGPs play a significant role in diverse cellular processes ranging from adhesion ...
Support Vector Machine Proteins Immunoglobulins Machine Learning Algorithms Deep Learning Computational Biology
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Machine Learning of ZnO Interaction with Immunoglobulins and Blood Proteins in Medicine.

Journal of healthcare engineering Mar 16, 2022
Toxoplasmosis is a zoonotic illness caused by . Those with a normal immune system normally recover without treatment. Immunocompromised individuals and pregnant women must be treated regularly. Toxoplasmosis is a serious illness that may reactivate i...
Metal Nanoparticles Zinc Oxide Toxoplasmosis Pregnancy Humans Immunoglobulins Female Machine Learning Zinc Retrospective Studies Blood Proteins
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Role of Soluble T-Cell Immunoglobulin Mucin Domain-3 in Differentiating Nontuberculous Mycobacterial Lung Disease from Pulmonary Colonization.

Archivos de bronconeumologia Feb 24, 2021
BACKGROUND: Differentiating between nontuberculous mycobacterial lung disease (NTM-LD) and pulmonary NTM colonization (NTM-Col) is difficult. Compared with healthy controls, patients with NTM-LD generally present immune tolerance along with increased...
Hepatitis A Virus Cellular Receptor 2 Mycobacterium Infections, Nontuberculous Humans Immunoglobulins Programmed Cell Death 1 Receptor T-Lymphocytes Ligands Pneumonia Mucins
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Evaluation of the Classification Accuracy of the Kidney Biopsy Direct Immunofluorescence through Convolutional Neural Networks.

Clinical journal of the American Society of Nephrology : CJASN Sep 16, 2020
BACKGROUND AND OBJECTIVES: Immunohistopathology is an essential technique in the diagnostic workflow of a kidney biopsy. Deep learning is an effective tool in the elaboration of medical imaging. We wanted to evaluate the role of a convolutional neura...
Image Processing, Computer-Assisted Kidney Kidney Diseases Area Under Curve Adult Male Middle Aged ROC Curve Fluorescent Antibody Technique, Direct Complement C1q Immunoglobulin kappa-Chains Immunoglobulin lambda-Chains Biopsy Fibrinogen Immunoglobulins Complement C3 Humans Neural Networks, Computer Female Aged
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Regular cold water swimming during winter time affects resting hematological parameters and serum erythropoietin.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society Jan 30, 2020
Recreational winter swimming in cold sea water evokes body responses to regularly repeated cold water immersion. However, the understanding of adaptive changes is still limited and data regarding very short-term exposure to severe cold stress are sca...
Humans Female Seasons Erythropoietin Blood Platelets Male Hematocrit Erythrocytes Cold Temperature Middle Aged Immunoglobulins Rest Folic Acid Water Swimming Blood Cell Count Hemoglobins
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Rapid discrimination of multiple myeloma patients by artificial neural networks coupled with mass spectrometry of peripheral blood plasma.

Scientific reports May 28, 2019
Multiple myeloma (MM) is a highly heterogeneous disease of malignant plasma cells. Diagnosis and monitoring of MM patients is based on bone marrow biopsies and detection of abnormal immunoglobulin in serum and/or urine. However, biopsies have a singl...
Humans Neural Networks, Computer Artificial Intelligence Female Aged Bone Marrow Case-Control Studies Datasets as Topic Aged, 80 and over Metabolome Male Immunoglobulins Principal Component Analysis Middle Aged Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Metabolic Networks and Pathways Multiple Myeloma
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Capturing the differences between humoral immunity in the normal and tumor environments from repertoire-seq of B-cell receptors using supervised machine learning.

BMC bioinformatics May 28, 2019
BACKGROUND: The recent success of immunotherapy in treating tumors has attracted increasing interest in research related to the adaptive immune system in the tumor microenvironment. Recent advances in next-generation sequencing technology enabled the...
High-Throughput Nucleotide Sequencing Amino Acid Motifs Complementarity Determining Regions Receptors, Antigen, B-Cell Area Under Curve Supervised Machine Learning Amino Acid Sequence Immunoglobulins ROC Curve Immunity, Humoral Databases, Genetic Humans Algorithms Tumor Microenvironment
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Resistance gene identification from Larimichthys crocea with machine learning techniques.

Scientific reports Dec 6, 2016
The research on resistance genes (R-gene) plays a vital role in bioinformatics as it has the capability of coping with adverse changes in the external environment, which can form the corresponding resistance protein by transcription and translation. ...
Genome Disease Resistance Histocompatibility Antigens Cation Transport Proteins Machine Learning Datasets as Topic Animals Antimicrobial Cationic Peptides Gene Expression Regulation Immunity, Innate Perciformes Fish Proteins Fish Diseases Immunoglobulins Interferons
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