Deep learning-based classification of primary bone tumors on radiographs: A preliminary study.

Journal: EBioMedicine
Published Date:

Abstract

BACKGROUND: To develop a deep learning model to classify primary bone tumors from preoperative radiographs and compare performance with radiologists.

Authors

  • Yu He
    Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, College of Chemistry, Fuzhou University, Fuzhou, Fujian, 350116, China.
  • Ian Pan
    Warren Alpert Medical School, Brown University, Providence, RI.
  • Bingting Bao
    Department of Radiology, The Second Xiangya Hospital of Central South University, No.139 Middle Renmin Road, Changsha, Hunan 410011, PR China.
  • Kasey Halsey
    From the Department of Radiology, Xiangya Hospital, Central South University, Changsha 410008, China (H.X.B., Z.X., D.C.W., W.H.L.); Department of Diagnostic Imaging, Rhode Island Hospital, Providence, RI (H.X.B., B.H., K.H., I.P., M.K.A.); Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pa (R.W.); Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology. Massachusetts General Hospital, Boston, Mass (K.C.); Warren Alpert Medical School at Brown University, Providence, RI (H.X.B., K.H., T.M.L.T., J.W.C., I.P.); Department of Radiology, Yongzhou Central Hospital, Yongzhou, China (L.B.S.); Department of Radiology, Changde Second People's Hospital, Changde, China (J.M.); Department of Radiology, Affiliated Nan Hua Hospital, University of South China, Hengyang, China (X.L.J.); Department of Radiology, Loudi Central Hospital, Loudi, China (Q.H.Z.); Department of Radiology, Chenzhou Second People's Hospital, Chenzhou, China (P.F.H.); Department of Radiology, Zhuzhou Central Hospital, Zhuzhou, China (Y.H.L.); Department of Radiology, Yiyang City Center Hospital, Yiyang, China (F.X.F.); Department of Radiology, Brigham and Women's Hospital, Boston, Mass (R.Y.H.); Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, Pa (R.S.); and Department of Radiology, The First Hospital of Changsha, Changsha, China (Q.Z.Y.).
  • Marcello Chang
    Stanford School of Medicine, Palo Alto, California.
  • Hui Liu
    Institute of Urology and Nephrology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
  • Shuping Peng
    Department of Radiology, The Second Xiangya Hospital of Central South University, No.139 Middle Renmin Road, Changsha, Hunan 410011, PR China.
  • Ronnie A Sebro
    Musculoskeletal Imaging, Department of Radiology, University of Pennsylvania, Philadelphia 19104, USA.
  • Jing Guan
    Department of Radiology, The Second Xiangya Hospital of Central South University, No.139 Middle Renmin Road, Changsha, Hunan 410011, PR China.
  • Thomas Yi
    Warren Alpert Medical School at Brown University, Providence, RI, USA.
  • Andrew T Delworth
    Brown University, Providence 02912, USA.
  • Feyisope Eweje
    Perelman School of Medicine at the University of Pennsylvania, Philadelphia 19104, USA.
  • Lisa J States
    Department of Radiology, Children's Hospital of Philadelphia, 19104, USA.
  • Paul J Zhang
    Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
  • Zishu Zhang
    Department of Radiology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China. S.Stavropoulos@uphs.upenn.edu Harrison_Bai@Brown.edu zishuzhang@csu.edu.cn.
  • Jing Wu
    School of Pharmaceutical Science, Jiangnan University, Wuxi, 214122, Jiangsu, China.
  • Xianjing Peng
    Department of Radiology, Xiangya Hospital, Central South University, No.87 Xiangya Road, Changsha, Hunan 410008, PR China. Electronic address: pengxianjing@csu.edu.cn.
  • Harrison X Bai
    Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.