Deep learning for classification of pediatric chest radiographs by WHO's standardized methodology.

Journal: PloS one
Published Date:

Abstract

BACKGROUND: The World Health Organization (WHO)-defined radiological pneumonia is a preferred endpoint in pneumococcal vaccine efficacy and effectiveness studies in children. Automating the WHO methodology may support more widespread application of this endpoint.

Authors

  • Yiyun Chen
    School of Resource and Environmental Sciences, Wuhan University, Wuhan 430079, China; State Key Laboratory of Soil and Sustainable Agriculture, Chinese Academy of Sciences, Nanjing 210008, China. Electronic address: chenyy@whu.edu.cn.
  • Craig S Roberts
    Merck & Co., Inc., Kenilworth, New Jersey, United States of America.
  • Wanmei Ou
    Merck & Co., Inc., Kenilworth, New Jersey, United States of America.
  • Tanaz Petigara
    Merck & Co., Inc., Kenilworth, New Jersey, United States of America.
  • Gregory V Goldmacher
    Merck & Co., Inc., Kenilworth, New Jersey, United States of America.
  • Nicholas Fancourt
    Menzies School of Health Research, Charles Darwin University, Darwin, Australia.
  • Maria Deloria Knoll
    Department of International Health, International Vaccine Access Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.