Quantification of Key Retinal Features in Early and Late Age-Related Macular Degeneration Using Deep Learning.

Journal: American journal of ophthalmology
PMID:

Abstract

PURPOSE: We sought to develop and validate a deep learning model for segmentation of 13 features associated with neovascular and atrophic age-related macular degeneration (AMD).

Authors

  • Bart Liefers
    Diagnostic Image Analysis Group, Department of Radiology, Radboud University Medical Center, Nijmegen, The Netherlands; Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address: Bart.Liefers@radboudumc.nl.
  • Paul Taylor
    London, United Kingdom.
  • Abdulrahman Alsaedi
    College of Medicine, Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi Arabia; Moorfields Eye Hospital NHS Foundation Trust, London.
  • Clare Bailey
    University Hospitals Bristol NHS Foundation Trust, Bristol.
  • Konstantinos Balaskas
    School of Pharmacy and Optometry, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom; Manchester Royal Eye Hospital, NHS Central Manchester University Hospitals, Manchester, United Kingdom.
  • Narendra Dhingra
    Mid Yorkshire Hospitals NHS Trust, Southampton.
  • Catherine A Egan
    Moorfields Eye Hospital National Health Service Foundation Trust, London, United Kingdom.
  • Filipa Gomes Rodrigues
    Moorfields Eye Hospital NHS Foundation Trust, London; National Institute for Health Research Biomedical Research Centre at Moorfields Eye Hospital National Health Service (NHS) Foundation Trust, UCL Institute of Ophthalmology, London.
  • Cristina González Gonzalo
    A-eye Research Group, Diagnostic Image Analysis Group, Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands; Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Tjebo F C Heeren
    Moorfields Eye Hospital National Health Service Foundation Trust, London, United Kingdom.
  • Andrew Lotery
    Faculty of Medicine, University of Southampton, Southampton.
  • Philipp L Müller
    Universitäts-Augenklinik Bonn, Bonn, Deutschland.
  • Abraham Olvera-Barrios
    Medical Retina, Moorfields Eye Hospital NHS Foundation Trust, London, UK a.olvera@nhs.net.
  • Bobby Paul
    Barking, Havering and Redbridge University Hospitals NHS Trust, Romford, United Kingdom.
  • Roy Schwartz
    Moorfields Eye Hospital NHS Foundation Trust, London.
  • Darren S Thomas
    Institute of Health Informatics, University College London (UCL), London, UK.
  • Alasdair N Warwick
    Moorfields Eye Hospital NHS Foundation Trust, London; Institute of Cardiovascular Science, University College London, London.
  • Adnan Tufail
    London, United Kingdom. Electronic address: Adnan.Tufail@moorfields.nhs.uk.
  • Clara I Sanchez