Deep learning for brain disorders: from data processing to disease treatment.

Journal: Briefings in bioinformatics
Published Date:

Abstract

In order to reach precision medicine and improve patients' quality of life, machine learning is increasingly used in medicine. Brain disorders are often complex and heterogeneous, and several modalities such as demographic, clinical, imaging, genetics and environmental data have been studied to improve their understanding. Deep learning, a subpart of machine learning, provides complex algorithms that can learn from such various data. It has become state of the art in numerous fields, including computer vision and natural language processing, and is also growingly applied in medicine. In this article, we review the use of deep learning for brain disorders. More specifically, we identify the main applications, the concerned disorders and the types of architectures and data used. Finally, we provide guidelines to bridge the gap between research studies and clinical routine.

Authors

  • Ninon Burgos
    Sorbonne Université, Institut du Cerveau - Paris Brain Institute - ICM, CNRS, Inria, Inserm, AP-HP, Hôpital de la Pitié-Salpêtrière, Paris 75013, France. Electronic address: ninon.burgos@cnrs.fr.
  • Simona Bottani
    Sorbonne Université, Institut du Cerveau - Paris Brain Institute - ICM, CNRS, Inria, Inserm, AP-HP, Hôpital de la Pitié-Salpêtrière, Paris 75013, France.
  • Johann Faouzi
    Paris Brain Institute, in the ARAMIS Lab.
  • Elina Thibeau-Sutre
    Paris Brain Institute, in the ARAMIS Lab.
  • Olivier Colliot
    Sorbonne Université, Institut du Cerveau - Paris Brain Institute - ICM, CNRS, Inria, Inserm, AP-HP, Hôpital de la Pitié-Salpêtrière, Paris 75013, France.