Identification of Novel Noninvasive Diagnostics Biomarkers in the Parkinson's Diseases and Improving the Disease Classification Using Support Vector Machine.

Journal: BioMed research international
Published Date:

Abstract

BACKGROUND: Parkinson's disease (PD) is a neurological disorder that is marked by the deficit of neurons in the midbrain that changes motor and cognitive function. In the substantia nigra, the selective demise of dopamine-producing neurons was the main cause of this disease. The purpose of this research was to discover genes involved in PD development.

Authors

  • Shadi Moradi
    Department of Medical Immunology, School of Medicine, Hamadan University of Medical Science, Hamadan, Iran.
  • Leili Tapak
    Modeling of Noncommunicable Diseases Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
  • Saeid Afshar
    Research Center for Molecular Medicine, Hamadan University of Medical Science, Hamadan, Iran.