Effect of simvastatin on the SIRT2/NF-κB pathway in rats with acute pulmonary embolism.

Journal: Pharmaceutical biology
PMID: 31070532

Abstract

CONTEXT: Statins have been widely used in acute pulmonary embolism (APE), while simvastatin has been well-established for the prevention of pulmonary hypertension, which was supposed to be an attractive recommendation for APE treatment.

Authors

  • Zhi-Yao Wu
    a Department of Respiratory Medicine (Department of Respiratory and Critical Care Medicine), National Key Clinical Specialty, Xiangya Hospital , Central South University , Changsha , China.
  • Hui Li
    Department of Ophthalmology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
  • Yong-Jun Tang
    a Department of Respiratory Medicine (Department of Respiratory and Critical Care Medicine), National Key Clinical Specialty, Xiangya Hospital , Central South University , Changsha , China.

Keywords

External Resources

Popular Topics
Recent Journals