Point-of-care screening for heart failure with reduced ejection fraction using artificial intelligence during ECG-enabled stethoscope examination in London, UK: a prospective, observational, multicentre study.

Journal: The Lancet. Digital health
PMID: 34998740

Abstract

BACKGROUND: Most patients who have heart failure with a reduced ejection fraction, when left ventricular ejection fraction (LVEF) is 40% or lower, are diagnosed in hospital. This is despite previous presentations to primary care with symptoms. We aimed to test an artificial intelligence (AI) algorithm applied to a single-lead ECG, recorded during ECG-enabled stethoscope examination, to validate a potential point-of-care screening tool for LVEF of 40% or lower.

Authors

  • Patrik Bachtiger
    Department of Health Policy and Management, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
  • Camille F Petri
    National Heart and Lung Institute and Centre for Cardiac Engineering, Imperial College London, London, UK; UKRI Centre for Doctoral Training in AI for Healthcare, Imperial College London, London, UK.
  • Francesca E Scott
    National Heart and Lung Institute and Centre for Cardiac Engineering, Imperial College London, London, UK.
  • Se Ri Park
    National Heart and Lung Institute and Centre for Cardiac Engineering, Imperial College London, London, UK.
  • Mihir A Kelshiker
    National Heart and Lung Institute and Centre for Cardiac Engineering, Imperial College London, London, UK; Imperial College Healthcare NHS Trust, London, UK.
  • Harpreet K Sahemey
    Imperial College Healthcare NHS Trust, London, UK.
  • Bianca Dumea
    Imperial College Healthcare NHS Trust, London, UK.
  • Regine Alquero
    Imperial College Healthcare NHS Trust, London, UK.
  • Pritpal S Padam
    Imperial College Healthcare NHS Trust, London, UK.
  • Isobel R Hatrick
    Imperial College Healthcare NHS Trust, London, UK.
  • Alfa Ali
    Imperial College Healthcare NHS Trust, London, UK.
  • Maria Ribeiro
    Imperial College Healthcare NHS Trust, London, UK.
  • Wing-See Cheung
    Imperial College Healthcare NHS Trust, London, UK.
  • Nina Bual
    Imperial College Healthcare NHS Trust, London, UK.
  • Bushra Rana
    Charing Cross Hospital, London (G.D.C., B.R.).
  • Matthew Shun-Shin
    Department of Computing, National Heart and Lung Institute, Imperial College London, Imperial College Healthcare NHS Trust, London, UK.
  • Daniel B Kramer
    Richard A. and Susan F. Smith Center for Outcomes Research, Division of Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America.
  • Alex Fragoyannis
    NHS Ealing Clinical Commissioning Group, London, UK.
  • Daniel Keene
    National Heart and Lung Institute, Hammersmith Campus, Imperial College London, 72 Du Cane Road, W12 0HS, London, UK.
  • Carla M Plymen
    Imperial College Healthcare NHS Trust, London, UK.
  • Nicholas S Peters
    National Heart and Lung Institute, Hammersmith Campus, Imperial College London, 72 Du Cane Road, W12 0HS, London, UK.

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