Development and Application of a Machine Learning Approach to Assess Short-term Mortality Risk Among Patients With Cancer Starting Chemotherapy.

Journal: JAMA network open
Published Date:

Abstract

IMPORTANCE: Patients with cancer who die soon after starting chemotherapy incur costs of treatment without the benefits. Accurately predicting mortality risk before administering chemotherapy is important, but few patient data-driven tools exist.

Authors

  • Aymen A Elfiky
    Dimitris Bertsimas, Jack Dunn, Colin Pawlowski, John Silberholz, Alexander Weinstein, and Ying Daisy Zhuo, Massachusetts Institute of Technology, Cambridge; Eddy Chen, Massachusetts General Hospital Cancer Center; Harvard Medical School; Aymen A. Elfiky, Dana-Farber Cancer Institute; Brigham and Women's Hospital; Harvard Medical School, Boston, MA.
  • Maximilian J Pany
    Brigham and Women's Hospital, Boston, Massachusetts.
  • Ravi B Parikh
    Division of Hematology and Oncology, Perelman School of Medicine, University of Philadelphia, Philadelphia, Pennsylvania.
  • Ziad Obermeyer
    Brigham and Women's Hospital, Boston, Massachusetts.