Kaempferol modulates Angiopoietin-like protein 2 expression to lessen the mastitis in mice.

Journal: Pharmacological reports : PR
PMID: 29627690

Abstract

BACKGROUND: Mastitis is inflammation of a breast (or udder). Angiopoietin-like protein 2 (ANGPTL2) has been found as a key inflammatory mediator in mastitis. Purpose of this research was to investigate the mechanisms about repressing effect of kaempferol on mastitis.

Authors

  • Hong-Bo Xiao
    College of Veterinary Medicine, Hunan Agricultural University, Changsha, China. Electronic address: xhbzhb@yahoo.com.
  • Guo-Guang Sui
    College of Veterinary Medicine, Hunan Agricultural University, Changsha, China.
  • Xiang-Yang Lu
    Hunan Province University Key Laboratory for Agricultural Biochemistry and Biotransformation, Hunan Agricultural University, Changsha, China; Hunan Co-Innovation Center for Ultilization of Botanical Functional Ingredients, Changsha, China.
  • Zhi-Liang Sun
    Biological Veterinary Drugs Branch, National Research Center of Engineering and Technology for Utilization of Botanical Functional Ingredients, Hunan Agricultural University, Changsha, China.

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