Experimental drugs in clinical trials for COPD: artificial intelligence via machine learning approach to predict the successful advance from early-stage development to approval.

Journal: Expert opinion on investigational drugs
PMID:

Abstract

INTRODUCTION: Therapeutic advances in drug therapy of chronic obstructive pulmonary disease (COPD) really effective in suppressing the pathological processes underlying the disease deterioration are still needed. Artificial Intelligence (AI) via Machine Learning (ML) may represent an effective tool to predict clinical development of investigational agents.

Authors

  • Luigino Calzetta
    Department of Medicine and Surgery, University of Parma, Parma, Italy.
  • Elena Pistocchini
    Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.
  • Alfredo Chetta
    Department of Medicine and Surgery, University of Parma, Parma, Italy.
  • Paola Rogliani
    Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.
  • Mario Cazzola
    Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.