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Adrenergic beta-2 Receptor Agonists

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A randomised, phase III trial of once-daily fluticasone furoate/vilanterol 100/25 μg versus once-daily vilanterol 25 μg to evaluate the contribution on lung function of fluticasone furoate in the combination in patients with COPD.

Respiratory medicine 28137501
BACKGROUND: The contribution of fluticasone furoate (FF) on lung function in the FF/vilanterol (VI) 100/25 μg combination has been demonstrated numerically, but not statistically.
Administration, Inhalation Adrenergic beta-2 Receptor Agonists Adult Aged Androstadienes Benzyl Alcohols Chlorobenzenes Double-Blind Method Drug Administration Schedule Drug Combinations Female Forced Expiratory Volume Glucocorticoids Humans Kaplan-Meier Estimate Male Middle Aged Pulmonary Disease, Chronic Obstructive Quality of Life
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Step up to triple therapy versus switch to dual bronchodilator therapy in patients with COPD on an inhaled corticosteroid/long-acting β-agonist: post-hoc analyses of KRONOS.

Respiratory research 40340809
BACKGROUND: In people with chronic obstructive pulmonary disease (COPD) on inhaled corticosteroid/long-acting β-agonist (ICS/LABA) therapy, the Global Initiative for Chronic Obstructive Lung Disease (GOLD) recommends stepping up to ICS/long-acting mu...
Administration, Inhalation Adrenal Cortex Hormones Adrenergic beta-2 Receptor Agonists Aged Bronchodilator Agents Double-Blind Method Drug Combinations Drug Substitution Drug Therapy, Combination Female Humans Male Middle Aged Muscarinic Antagonists Pulmonary Disease, Chronic Obstructive Treatment Outcome
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Experimental drugs in clinical trials for COPD: artificial intelligence via machine learning approach to predict the successful advance from early-stage development to approval.

Expert opinion on investigational drugs 37364225
INTRODUCTION: Therapeutic advances in drug therapy of chronic obstructive pulmonary disease (COPD) really effective in suppressing the pathological processes underlying the disease deterioration are still needed. Artificial Intelligence (AI) via Mach...
Administration, Inhalation Adrenergic beta-2 Receptor Agonists Artificial Intelligence Bayes Theorem Bronchodilator Agents Humans Machine Learning Muscarinic Antagonists Pulmonary Disease, Chronic Obstructive
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