Efficacy of eculizumab in an adult patient with HIV-associated hemolytic uremic syndrome: A case report.

Journal: Medicine

PMID: 29390523

Abstract

INTRODUCTION: Hemolytic uremic syndrome (HUS) in Human Immunodeficiency Virus (HIV)-positive patients has become a rare cause of kidney injury since the era of highly active antiretroviral therapy (HAART). Plasma exchange and antiretroviral therapy were previously recommended but often failed to achieve remission. We report a case of HUS in a HIV-positive patient treated successfully with eculizumab.

Authors

Marine Freist

Service de Néphrologie, Pôle REUNNIRH, CHU Clermont-Ferrand, Clermont-Ferrand Centre de Référence des Microangiopathies Thrombotiques, Paris Service d'anatomopathologie, CHU Clermont-Ferrand, Clermont-Ferrand Service d'Hématologie, Hôpital Saint-Antoine, CHU Paris Est, AP-HP Université Pierre et Marie Curie UPMC, Paris Service de Réanimation, Pôle REUNNIRH, CHU Clermont-Ferrand, Clermont-Ferrand, France.
Cyril Garrouste
Nora Szlavik
Paul Coppo
Alexandre Lautrette
Anne Elisabeth Heng

Keywords

Acute Kidney Injury Antibodies, Monoclonal Antibodies, Monoclonal, Humanized Antiretroviral Therapy, Highly Active Biopsy, Needle Female Follow-Up Studies Hemolytic-Uremic Syndrome HIV Infections Humans Immunohistochemistry Kidney Function Tests Middle Aged Plasma Exchange Renal Dialysis Risk Assessment Treatment Outcome

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View on PubMed Access via DOI PubMed (29390523)

Efficacy of eculizumab in an adult patient with HIV-associated hemolytic uremic syndrome: A case report.

Abstract

Authors

Keywords

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